Recent progress in histone deacetylase inhibitors as anticancer agents

L Cappellacci, DR Perinelli, F Maggi… - Current medicinal …, 2020 - ingentaconnect.com
Histone Deacetylase (HDAC) inhibitors are a relatively new class of anti-cancer agents that
play important roles in epigenetic or non-epigenetic regulation, inducing death, apoptosis …

[HTML][HTML] Effect of sodium butyrate on HDAC8 mRNA expression in colorectal cancer cell lines and molecular docking study of LHX1-sodium butyrate interaction

F Forouzesh, M Ghiaghi, H Rahimi - EXCLI journal, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common type of cancer and the fourth leading
cause of cancer related deaths worldwide. The Histone Deacetylase 8 (HDAC8) gene is a …

Screening of novel histone deacetylase 7 inhibitors through molecular docking followed by a combination of molecular dynamics simulations and ligand-based …

Y Yuan, Z Hu, M Bao, R Sun, X Long… - Journal of …, 2019 - Taylor & Francis
Histone acetylation/deacetylation is a key mechanism for transcription regulation which
plays an important role in control of gene expression, tissue growth, and development. In …

Exploring the potential binding sites of some known HDAC inhibitors on some HDAC8 conformers by docking studies

Y Sixto-López, JA Gómez-Vidal… - Applied biochemistry and …, 2014 - Springer
We describe the conformational behavior of histone deacetylase 8 (HDAC8) using
molecular dynamics (MD) simulations. HDAC8 conformers were used for the docking …

Histone deacetylase inhibitory properties of metabolites from leaves of Quercus pontica K. Koch and its metabolites

G Renda, S Sevgi, M Šoral, G Bora-Akoğlu… - International Journal …, 2024 - Taylor & Francis
The infusions prepared from some Quercus L. species are used in folk medicine for
medicinal purposes and consumed as tea. Quercus pontica K. Koch was selected in this …

QSAR study of chalcone derivatives as anti-Leishmania agents

M Iman, A Davood… - Turkish Journal of …, 2014 - journals.tubitak.gov.tr
Quantitative structure activity relationship analyses were used to identify the ideal
physicochemical characteristics of potential chalcone derivatives as anti-Leishmania agents …

Performance evaluation of congestion-aware routing protocols for underwater sensor networks with multimedia data

S Jain, ES Pilli, MC Govil… - 2015 IEEE Underwater …, 2015 - ieeexplore.ieee.org
Performance advancements in acoustic communication technology have fostered to provide
technical platform for numerous interdisciplinary applications ranging from bathymetry …

Desenvolvimento de híbridos de triazenos anti-tumorais

LMAP Ferreira - 2019 - search.proquest.com
As doenças cancerígenas são apresentadas como principais causas de morte por todo o
mundo. Apesar da evolução da terapêutica nos últimos anos, o Glioblastoma Multiforme e o …

[引用][C] Structure-based virtual screening and drug-like of quercetin derivatives with anti-malaria activity

A Rouane, N Tchouar, A Kerassa, S Belaidi, M Cinar - Reviews in Theoretical …, 2017