[HTML][HTML] Diabetes and cardiac autonomic neuropathy: clinical manifestations, cardiovascular consequences, diagnosis and treatment

AS Balcıoğlu, H Müderrisoğlu - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Cardiac autonomic neuropathy (CAN) is a frequent chronic complication of diabetes mellitus
with potentially life-threatening outcomes. CAN is caused by the impairment of the …

[HTML][HTML] Preliminary evidence for the presence of multiple forms of cell death in diabetes cardiomyopathy

J Wei, Y Zhao, H Liang, W Du, L Wang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Diabetic mellitus (DM) is a common degenerative chronic metabolic disease often
accompanied by severe cardiovascular complications (DCCs) as major causes of death in …

Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism

D Wang, P Luo, Y Wang, W Li, C Wang, D Sun… - Diabetes, 2013 - Am Diabetes Assoc
Impaired cardiac microvascular function contributes to cardiovascular complications in
diabetes. Glucagon-like peptide-1 (GLP-1) exhibits potential cardioprotective properties in …

[HTML][HTML] Rutin alleviates diabetic cardiomyopathy in a rat model of type 2 diabetes

YB Wang, ZM Ge, WQ Kang… - Experimental and …, 2015 - spandidos-publications.com
Diabetic cardiomyopathy (DCM), an independent coronary heart disease that develops in
diabetic individuals, is characterized by changes in the myocardial structure and function …

AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases

Q Lu, X Li, J Liu, X Sun, T Rousselle, D Ren… - Bioscience …, 2019 - portlandpress.com
Diabetics have higher morbidity and mortality in cardiovascular disease (CVD). A variety of
antidiabetic agents are available for clinical choice. Cardiovascular (CV) safety assessment …

Exendin‐4 and liraglutide attenuate glucose toxicity‐induced cardiac injury through mTOR/ULK1‐dependent autophagy

W Yu, W Zha, J Ren - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Mitochondrial injury and defective autophagy are common in diabetic cardiomyopathy.
Recent evidence supports benefits of glucagon‐like peptide‐1 (GLP‐1) agonists exendin‐4 …

[HTML][HTML] Cardioprotective effects of exenatide against oxidative stress-induced injury

G Chang, D Zhang, H Yu, P Zhang… - International …, 2013 - spandidos-publications.com
Myocardial ischemia/reperfusion (MI/R) leads to oxidative stress, which may in turn lead to
myocardial injury. In the present study, we investigated the effects of exenatide, a glucagon …

Protective effects of sitagliptin on myocardial injury and cardiac function in an ischemia/reperfusion rat model

G Chang, P Zhang, L Ye, K Lu, Y Wang, Q Duan… - European journal of …, 2013 - Elsevier
The purpose of this study is to investigate the effects and the underlying mechanisms of
sitagliptin pretreatment on myocardial injury and cardiac function in myocardial …

Physiological and pharmacological roles of FGF21 in cardiovascular diseases

P Cheng, F Zhang, L Yu, X Lin, L He… - Journal of Diabetes …, 2016 - Wiley Online Library
Cardiovascular disease (CVD) is one of the most severe diseases in clinics. Fibroblast
growth factor 21 (FGF21) is regarded as an important metabolic regulator playing a …

[HTML][HTML] Cardioprotection by exenatide: A novel mechanism via improving mitochondrial function involving the GLP-1 receptor/cAMP/PKA pathway

G Chang, J Liu, S Qin, Y Jiang… - International …, 2018 - spandidos-publications.com
Accumulating evidence suggests that glucagon-like peptide-1 (GLP-1) and its analogues
exert cardioprotective effects via modulating cardiomyocyte metabolism. Mitochondria play a …