Localization and targeting of voltage-dependent ion channels in mammalian central neurons

H Vacher, DP Mohapatra… - Physiological …, 2008 - journals.physiology.org
The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

Inward rectifier potassium channels

CG Nichols, AN Lopatin - Annual review of physiology, 1997 - annualreviews.org
▪ Abstract The past three years have seen remarkable progress in research on the molecular
basis of inward rectification, with significant implications for basic understanding and …

[图书][B] Neuronal dynamics: From single neurons to networks and models of cognition

W Gerstner, WM Kistler, R Naud, L Paninski - 2014 - books.google.com
What happens in our brain when we make a decision? What triggers a neuron to send out a
signal? What is the neural code? This textbook for advanced undergraduate and beginning …

Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties

E Hay, S Hill, F Schürmann, H Markram… - PLoS computational …, 2011 - journals.plos.org
The thick-tufted layer 5b pyramidal cell extends its dendritic tree to all six layers of the
mammalian neocortex and serves as a major building block for the cortical column. L5b …

Inactivation properties of voltage-gated K+ channels altered by presence of β-subunit

J Rettig, SH Heinemann, F Wunder, C Lorra, DN Parcej… - Nature, 1994 - nature.com
Structural and functional diversity of voltage-gated Kv1-type potassium channels in rat brain
is enhanced by the association of two different types of subunits, the membrane-bound, pore …

Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity

JS Trimmer - Neuron, 2015 - cell.com
Potassium channels (KChs) are the most diverse ion channels, in part due to extensive
combinatorial assembly of a large number of principal and auxiliary subunits into an …

Localization of voltage-gated ion channels in mammalian brain

JS Trimmer, KJ Rhodes - Annu. Rev. Physiol., 2004 - annualreviews.org
▪ Abstract The intrinsic electrical properties of neurons are shaped in large part by the action
of voltage-gated ion channels. Molecular cloning studies have revealed a large family of ion …

Kv3 channels: enablers of rapid firing, neurotransmitter release, and neuronal endurance

LK Kaczmarek, Y Zhang - Physiological reviews, 2017 - journals.physiology.org
The intrinsic electrical characteristics of different types of neurons are shaped by the K+
channels they express. From among the more than 70 different K+ channel genes …

Functional and molecular differences between voltage-gated K+ channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus

M Martina, JH Schultz, H Ehmke… - Journal of …, 1998 - Soc Neuroscience
We have examined gating and pharmacological characteristics of somatic K+ channels in
fast-spiking interneurons and regularly spiking principal neurons of hippocampal slices. In …

Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons

CC Lien, P Jonas - Journal of Neuroscience, 2003 - Soc Neuroscience
Kv3 channels are thought to be essential for the fast-spiking (FS) phenotype in GABAergic
interneurons, but how these channels confer the ability to generate action potentials (APs) at …