The NLRP3 inflammasome in non-alcoholic fatty liver disease and steatohepatitis: Therapeutic targets and treatment

L Yu, W Hong, S Lu, Y Li, Y Guan, X Weng… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent primary liver
diseases worldwide and can develop into various conditions, ranging from simple steatosis …

Radical oxygen species: an important breakthrough point for botanical drugs to regulate oxidative stress and treat the disorder of glycolipid metabolism

M Luo, Y Zheng, S Tang, L Gu, Y Zhu, R Ying… - Frontiers in …, 2023 - frontiersin.org
Background: The incidence of glycolipid metabolic diseases is extremely high worldwide,
which greatly hinders people's life expectancy and patients' quality of life. Oxidative stress …

Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis

M Chen, Y Xie, S Gong, Y Wang, H Yu, T Zhou… - Pharmacological …, 2021 - Elsevier
Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease in clinical practice. It
has been considered that NASH is one of the main causes of chronic liver disease, cirrhosis …

Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity

Y Cao, S Yue, A Wang, L Xu, Y Hu, X Qiao… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Nonalcoholic fatty liver disease (NAFLD) is a prevalent
liver disease, but currently has no specific medication in clinic. Antrodia cinnamomea (AC) is …

Research and progress of inflammasomes in nonalcoholic fatty liver disease

K Chen, B Ke, L Cheng, X Yu, Z Wang… - International …, 2023 - Elsevier
With the development of the social economy, unhealthy living habits and eating styles are
gradually affecting people's health in recent years. As a chronic liver disease, NAFLD is …

Pharmacological effects of Chinese medicine modulating NLRP3 inflammasomes in fatty liver treatment

T Liu, G Xu, L Liang, X Xiao, Y Zhao… - Frontiers in Pharmacology, 2022 - frontiersin.org
Inflammation is a key contributing factor in the pathogenesis of fatty liver diseases (FLD),
such as nonalcoholic fatty liver disease (NAFLD) and alcohol-associated liver diseases …

The role and mechanism of pyroptosis and potential therapeutic targets in non-alcoholic fatty liver disease (NAFLD)

SJ Li, AB Liu, YY Yu, JH Ma - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a clinical pathological syndrome characterized
by the excessive accumulation of fat within liver cells, which can progress to end-stage liver …

Antrodia cinnamomea prevents ovariectomized‐promoted bone loss by inhibiting osteoclast formation

C Po‐Chun, HK Su, SC Liu, LHH Thuong… - Environmental …, 2024 - Wiley Online Library
Osteoporosis is a common bone disease in aging populations, particularly in
postmenopausal women. Anti‐resorptive and anabolic drugs have been applied to prevent …

Antrodia cinnamomea Extract Attenuates Cisplatin‐Induced Muscle Atrophy, Apoptosis, and Cell Growth Suppression

SM Liang, CL Kuo, YJ Lu, TC Chang… - Journal of Food …, 2023 - Wiley Online Library
Antrodia cinnamomea (AC), a potential medicinal fungus which possesses anti‐
inflammatory and anticancer activities, has been previously reported to be able to ameliorate …

Antrodia cinnamomea May Interfere with the Interaction Between ACE2 and SARS-CoV-2 Spike Protein in vitro and Reduces Lung Inflammation in a Hamster Model …

LH Li, HW Chiu, WT Wong, KC Huang… - Journal of …, 2023 - Taylor & Francis
Purpose Coronavirus disease 2019 (COVID-19) poses a global health challenge with
widespread transmission. Growing concerns about vaccine side effects, diminishing efficacy …