The NOTCH gene was identified approximately 110 years ago. Classical studies have
revealed that NOTCH signaling is an evolutionarily conserved pathway. NOTCH receptors …

Systemic sclerosis (SSc) is a prototypical inflammatory fibrotic disease involving
inflammation, vascular abnormalities and fibrosis that primarily affect the skin and lungs. The …

The enhancer of zeste homolog 2 (EZH2) is encoded by the Enhancer of zeste 2 polycomb
repressive complex 2 subunit gene. EZH2 is involved in the cell cycle, DNA damage repair …

Abstract N6-methyladenosine (m6A) is the most prevalent RNA modification at the
posttranscriptional level and involved in various diseases and cellular processes. However …

Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast
function play critical roles in bone formation, which is a highly regulated process. Long …

Simple Summary This review aimed to describe the contribution of functional interaction
between the lncRNA HOTAIR and microRNAs in human diseases, including cancer …

The Notch signaling pathway is an evolutionarily conserved pathway that modulates normal
biological processes involved in cellular differentiation, apoptosis, and stem cell self …

Systemic sclerosis is a rare and chronic connective tissue disease with a multifaceted
pathogenesis characterised by heterogeneous multi-organ clinical manifestations. Every …

Fibrosis can be defined as an excessive and deregulated deposition of extracellular matrix
proteins, causing loss of physiological architecture and dysfunction of different tissues and …

Diabetes is a metabolic disorder and its incidence is still increasing. Diabetic vascular
complications cause major diabetic mobility and include accelerated atherosclerosis …