The application of clustered regularly interspaced short palindromic repeats (CRISPR) for
genetic manipulation has revolutionized life science over the past few years. CRISPR was …

The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

Aging is an inevitable biological process characterized by a progressive decline in
physiological function and increased susceptibility to disease. The detrimental effects of …

DNA molecules in mitochondria, just like those in the nucleus of eukaryotic cells, are
constantly damaged by noxious agents. Eukaryotic cells have developed efficient …

Mitochondrial disease refers to a heterogeneous group of disorders resulting in defective
cellular energy production due to abnormal oxidative phosphorylation (oxphos). Primary …

Seeds are an important life cycle stage because they guarantee plant survival in
unfavorable environmental conditions and the transfer of genetic information from parents to …

Plant mitochondria have a complex and peculiar genetic system. They have the largest
genomes, as compared to organelles from other eukaryotic organisms. These can expand …

Considerable efforts have been made to understand the role of oxidative stress in age‐
related diseases and ageing. The mitochondrial free radical theory of ageing, which …

Reactive oxygen species (ROS) play an essential role in the regulation of seed dormancy,
germination, and deterioration in plants. The low level of ROS as signaling particles …

Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease
affecting thousands of people in the world and effective treatment is still not available. Over …