Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Exosomes are endosomal-derived vesicles that play a critical role in cell-to-cell
communication and are secreted in several biological fluids including serum, saliva, urine …

Exosomes are a subset of extracellular vesicles and their size is approximately 100 nm in
diameter. They are surrounded by a lipid bilayer membrane and secreted from almost all of …

Tumor progression involves invasion, migration, metabolism, autophagy, exosome
secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie …

Ovarian cancer is largely diagnosed at advanced stages upon detection of multiple
peritoneal dissemination, resulting in poor outcomes. CD47 is overexpressed in tumors …

Exosomes, a type of extracellular vesicle with a diameter of approximately 100 nm that is
secreted by all cells, regulate the phenotype and function of recipient cells by carrying …

Exosomes are present within the local hypoxic tumor microenvironment, where they are able
to transfer microRNAs between cells, thereby, effectively mediating cell-cell communication …

The fate of leukaemia stem cells (LSCs) is determined by both their inherent mechanisms
and crosstalk with their niches. Although LSCs were confirmed to be eradicated by restarting …

High cancer mortality is attributed to metastasis to a large extent. However, cancer
metastasis remains devoid of dynamic monitoring and early prevention in terms of current …