There is a rise in the number of people who have vision loss due to retinal diseases, and
conventional therapies for treating retinal degeneration fail to repair and regenerate the …

Retinal degenerative diseases, such as age-related macular degeneration, retinitis
pigmentosa, diabetic retinopathy or glaucoma, represent the main causes of a decreased …

Mesenchymal stem cell-derived exosomes have been under investigation as potential
treatments for a diverse range of diseases, and many animal and clinical trials have …

Extracellular vesicles (EVs) have been recognized as promising candidates for developing
novel therapeutics for a wide range of pathologies, including ocular disorders, due to their …

Retinitis pigmentosa, defined more properly as cone–rod dystrophy, is a paradigm of
inherited diffuse retinal dystrophies, one of the rare diseases with the highest prevalence in …

Abstract ENGLISH SUMMARY Dry eye disease (DED) is characterized by ocular dryness,
irritation and blurred vision and has a significant impact on the patient's quality of life. This …

Purpose There is a growing interest in extracellular vesicles (EVs) for ocular applications as
therapeutics, biomarkers, and drug delivery vehicles. EVs secreted from mesenchymal stem …

Stem cell therapies hold great promise as alternative treatments for incurable optic nerve
disorders. Although mesenchymal stem cells exhibit various tissue regeneration and …

Mitochondrial diseases disrupt cellular energy production and are among the most complex
group of inherited genetic disorders. Affecting approximately 1 in 5000 live births, they are …

Mesenchymal stem cell (MSC) therapy has been investigated intensively for many years.
However, there is a potential risk related to MSC applications in various cell niches …