Control of aflatoxin biosynthesis by sulfur containing benzimidazole derivatives: In-silico interaction, biological activity, and gene regulation of Aspergillus flavus

P Dhanamjayulu, RB Boga, R Das, A Mehta - Journal of Biotechnology, 2023 - Elsevier
Aspergillus flavus producing aflatoxins is one of the potent contaminants of raw food
commodities during pre-and post-harvest crops. Aflatoxins are the group of secondary …

In-Vitro and in-silico investigation for the spent-coffee bioactive phenolics as a promising aflatoxins production inhibitor

A Farouk, T Alsulami, HS Ali, AN Badr - Toxins, 2023 - mdpi.com
Aflatoxin, is a naturally occurring polyketide generated by Aspergillus flavus via biosynthetic
pathways, including polyketide synthase (PKS) and non-ribosomal enzymes. The in vitro …

Integrated in vivo and in silico evaluation of sweet basil oil as a protective agent against cisplatin-induced neurotoxicity in mice

DS Mohamed, O Shehata, MM Labib… - Beni-Suef University …, 2023 - Springer
Background Cisplatin is a wide-ranging antineoplastic drug. Neurotoxicity is one of
cisplatin's side effects that restrict its usage. This study aimed to investigate the possible …

[HTML][HTML] The Intervention of oil constituents from Garcinia kola against epidermal growth factor receptor in breast cancer using in-silico analysis

AD Folayan, JK Akintunde, AJ Akamo… - Informatics in Medicine …, 2023 - Elsevier
Abstract Background Using GC-MS and in-silico analysis, this study is aimed at investigating
the potential anti-cancer properties of Garcinia kola oil constituents. Objective Epidermal …

Novel Insights into the Antimicrobial and Antibiofilm Activity of Pyrroloquinoline Quinone (PQQ); In Vitro, In Silico, and Shotgun Proteomic Studies

MM Labib, AM Alqahtani, HHA Nahas… - …, 2024 - pmc.ncbi.nlm.nih.gov
Microbial infections pose a significant global health threat, affecting millions of individuals
and leading to substantial mortality rates. The increasing resistance of microorganisms to …

Investigation and drug design for novel molecules from natural products as inhibitors for controlling multiple myeloma disease using in-silico tools

A Zari, LAF Kurdi, FA Jaber, KMS Alghamdi… - Journal of …, 2023 - Taylor & Francis
Multiple myeloma (MM) is a disease that causes plasma cell growth in the bone marrow and
immune globulin buildup in blood and urine. Despite recent advances in MM therapy, many …

Inhibition analysis of aflatoxin by in silico targeting the thioesterase domain of polyketide synthase enzyme in Aspergillus ssp

MM Labib, MK Amin, AM Alzohairy… - Journal of …, 2022 - Taylor & Francis
The spread of fungal growth causes enormous economic, agricultural, and health problems
for humans, such as Aspergillus sp., which produce aflatoxins. Thus, the inhibition of …

[PDF][PDF] In-Vitro and In-Silico Investigation for the Spent-Coffee Bioactive Phenolics as a Promising Aflatoxins Production Inhibitor. Toxins 2023, 15, 225

A Farouk, T Alsulami, HS Ali, AN Badr - 2023 - academia.edu
Aflatoxin, is a naturally occurring polyketide generated by Aspergillus flavus via biosynthetic
pathways, including polyketide synthase (PKS) and non-ribosomal enzymes. The in vitro …

Analysis of 3D structure of the protein of Haemophilus influenzae by homology modelling helps in predicting binding sites for substrate, leads to design antibiotic

R Rasool, M Shafiq, A Farid… - Journal of Ayub …, 2024 - jamc.ayubmed.edu.pk
Background: Haemophilus influenza persists as a well-known root of ill health in children
throughout the entire world. Before the introduction of the vaccine, Haemophilus influenza …

ANALYSIS OF INHIBITORY EFFECT OF TRANSCRIPTIONAL REGULATORY PROTEIN (STY 4289) OF SALMONELLA TYPHI CT18 BY HOMOLOGY MODELLING.

A Farid, S Sadiq, R Rasool, G Rasool… - Journal of Ayub …, 2023 - search.ebscohost.com
Background: Salmonella typhi cause typhoid fever which is life threatening disease. It affects
approximately 600,000 people per annum around the world. Food and water are the integral …