Plasminogen activator inhibitor type‐1 as a regulator of fibrosis

R Rabieian, M Boshtam, M Zareei… - Journal of cellular …, 2018 - Wiley Online Library
Fibrosis is known as a frequent and irreversible pathological condition which is associated
with organ failure. Tissue fibrosis is a central process in a variety of chronic progressive …

[HTML][HTML] The molecular mechanism of LRP1 in physiological vascular homeostasis and signal transduction pathways

Z He, G Wang, J Wu, Z Tang, M Luo - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Interactions between vascular smooth muscle cells (VSMCs), endothelial cells (ECs),
pericytes (PCs) and macrophages (MФ), the major components of blood vessels, play a …

The Roles of Fibrinolytic Factors in Bone Destruction Caused by Inflammation

Y Kanno - Cells, 2024 - mdpi.com
Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic
lupus erythematosus, Crohn's disease, periodontitis, and carcinoma metastasis frequently …

Inflammatory mediators in various molecular pathways involved in the development of pulmonary fibrosis

MF Muneesa, SB Shaikh, TM Jeena… - International …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a type of interstitial lung disease (ILD) that is marked by
scarring of lung tissue, ultimately leading to respiratory failure. The survival rate of IPF is …

Trichostatin A promotes esophageal squamous cell carcinoma cell migration and EMT through BRD4/ERK1/2‐dependent pathway

D Liu, Y Liu, B Qi, C Gu, S Huo, B Zhao - Cancer Medicine, 2021 - Wiley Online Library
Abstract Background Histone deacetylases (HDACs) have been demonstrated to be
aberrantly activated in tumorigenesis and cancer development. Thus, HDAC inhibitors …

Topical Administration of Heat-Killed Enterococcus faecalis Strain KH2 Promotes Re-Epithelialization and Granulation Tissue Formation during Skin Wound-Healing

H Tanno, E Kanno, S Kurosaka, Y Oikawa, T Watanabe… - Biomedicines, 2021 - mdpi.com
Lactic acid bacteria (LAB) are known to have beneficial effects on immune responses when
they are orally administered as bacterial products. Although the beneficial effects of LAB …

Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr925

B Thapa, BH Koo, YH Kim, HJ Kwon, DS Kim - … and biophysical research …, 2014 - Elsevier
Tumor-infiltrating macrophages are potential candidates for cancer immunotherapy.
However, the detailed molecular mechanism underlying macrophage infiltration into tumors …

[HTML][HTML] Expression of Bmi-1 and PAI-1 in esophageal squamous cell carcinoma

Y Zhang, YL Zhang, HM Chen, HW Pu… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To determine the correlation between invasiveness, migration and prognosis in
esophageal squamous cell carcinoma (ESCC) and expression of the B-cell-specific …

Potent anti-tumor immunostimulatory biocompatible nanohydrogel made from DNA

J Jiang, X Kong, Y Xie, H Zou, Q Tang, D Ma… - Nanoscale Research …, 2019 - Springer
Unmethylated CpG oligodeoxynucleotides are potent immunostimulatory motifs in activating
both innate and acquired immune system by inducing Th1 type antigen-specific T cell …

AC‐type CpG ODN accelerates wound healing via regulating fibroblasts and immune response

L Li, Z Xu, J Zuo, J Ding - Journal of cellular biochemistry, 2019 - Wiley Online Library
Abolished or delayed wound healing is a serious problem in clinical surgery, therefore, the
new therapy for wound healing is needed. Synthetic oligodeoxynucleotides containing one …