The involvement of long non-coding RNAs in bone

C Aurilia, S Donati, G Palmini, F Miglietta… - International journal of …, 2021 - mdpi.com
A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …

Osteomyelitis and non-coding RNAS: a new dimension in disease understanding

MS Hussain, NK Shaikh, M Agrawal, M Tufail… - … -Research and Practice, 2024 - Elsevier
Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to
its intricate etiology and limited treatment options. Despite strides in surgical and …

Fluid shear stress regulates osteoblast proliferation and apoptosis via the lncRNA TUG1/miR‐34a/FGFR1 axis

X Wang, J He, H Wang, D Zhao, B Geng… - Journal of cellular …, 2021 - Wiley Online Library
LncRNAs and microRNAs play critical roles in osteoblast differentiation and bone formation.
However, their exact roles in osteoblasts under fluid shear stress (FSS) and the possible …

Circ_0091702 serves as a sponge of miR-545-3p to attenuate sepsis-related acute kidney injury by upregulating THBS2

M Tan, R Bei - Journal of molecular histology, 2021 - Springer
Circular RNA (circRNA) has been shown to play an important function in the progression of
human diseases, including sepsis with acute kidney injury (AKI). However, the role and …

Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances

L Yan, L Liao, X Su - Progress in Orthodontics, 2022 - Springer
Orthodontic tooth movement relies on bone remodeling and periodontal tissue regeneration
in response to the complicated mechanical cues on the compressive and tensive side. In …

The Circ_0001367/miR-545-3p/LUZP1 Axis regulates cell proliferation, migration and invasion in glioma cells

X Dong, P Zhang, L Liu, H Li, S Cheng, S Li… - Frontiers in …, 2021 - frontiersin.org
Glioma is the most common primary intracranial malignant tumour in adults. It has a high
incidence and poses a serious threat to human health. Circular RNA is a hotspot of cancer …

circ_0000376 knockdown suppresses non-small cell lung cancer cell tumor properties by the miR-545-3p/PDPK1 pathway

C Sun, H Guan, J Li, Y Gu - Open Medicine, 2023 - degruyter.com
Non-small cell lung cancer (NSCLC) accounts for 80% of total lung cancers, which are the
main killer of cancer-related death worldwide. Circular RNA (circRNA) has been found to …

Long noncoding RNA LINC01410 suppresses tumorigenesis and enhances radiosensitivity in neuroblastoma cells through regulating miR-545-3p/HK2 axis

L Mou, L Wang, S Zhang, Q Wang - OncoTargets and therapy, 2021 - Taylor & Francis
Background Abnormal expression of long noncoding RNAs (lncRNAs) was often involved in
tumorigenesis and radiosensitivity of various cancers. The aim of this study was to explore …

Long non-coding RNAs in bone formation: Key regulators and therapeutic prospects

C Jiang, P Wang, ZW Tan, Y Zhang - Open Life Sciences, 2024 - degruyter.com
Recent scientific investigations have revealed the intricate mechanisms underlying bone
formation, emphasizing the essential role of long non-coding RNAs (lncRNAs) as critical …

Long non-coding TRPM2-AS regulates fracture healing by targeting miR-545-3p/Bmp2

R Kang, L Huang, T Zeng, J Ma, D Jin - Journal of Orthopaedic Surgery …, 2024 - Springer
Objective Delayed fracture healing increases the suffering of patients. An in-depth
investigation of the pathogenesis of delayed fracture healing may offer new direction for the …