Parkinson's disease (PD) is the second most common neurodegenerative disease, which
manifests with both motor and non-motor symptoms. Circadian rhythm dysregulation, as one …

The circadian rhythm (CR) is a set of autonomous endogenous oscillators. Exposure to the
24-hour day-night cycle synchronizes our CR system, maintaining homeostasis and human …

" The environment shapes people's actions," a well-known proverb, strongly dictates that a
change in our way of life changes our behavior. Circadian rhythms have been identified as a …

Apoptosis of vascular smooth muscle cells (VSMCs) accelerates manifestation of plaque
vulnerability in atherosclerosis. Long noncoding RNA NEAT1 participates in the proliferation …

In many organisms, circadian rhythms and associated oscillations in gene expression are
controlled by post-translational modifications of histone proteins. Although epigenetic …

Circadian rhythm disorders pose major risks to human health and animal production activity,
and the hypothalamus is the center of circadian rhythm regulation. However, the epigenetic …

LncRNAs are long non-coding RNAs that are widely recognized as crucial regulators of
gene expression and metabolic control, involved in numerous dormancy-related processes …

Emerging evidence has demonstrated that long noncoding RNAs (lncRNAs) play critical
roles in the epigenetic and transcriptional regulation of mammalian circadian systems …

Eukaryotic circadian rhythms are often attributed to transcription-translation feedback loops
(TTFLs). However, rhythms can still persist in the absence of functioning TTFLs. Our …

Neuron driven physiological activities such as sleep, feeding, energy consumption are
controlled by light sensitive central clock genes in the pacemaker neurons in the brain …