A review of feature selection methods for machine learning-based disease risk prediction

N Pudjihartono, T Fadason, AW Kempa-Liehr… - Frontiers in …, 2022 - frontiersin.org
Machine learning has shown utility in detecting patterns within large, unstructured, and
complex datasets. One of the promising applications of machine learning is in precision …

Statistical methodology in studies of prenatal exposure to mixtures of endocrine-disrupting chemicals: a review of existing approaches and new alternatives

N Lazarevic, AG Barnett, PD Sly… - Environmental health …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposures to endocrine-disrupting chemicals (EDCs) during critical
developmental windows have been implicated in the etiologies of a wide array of adverse …

Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression

JF Bobb, B Claus Henn, L Valeri, BA Coull - Environmental Health, 2018 - Springer
Background Estimating the health effects of multi-pollutant mixtures is of increasing interest
in environmental epidemiology. Recently, a new approach for estimating the health effects of …

Early-life environmental exposures and childhood obesity: an exposome-wide approach

M Vrijheid, S Fossati, L Maitre, S Márquez… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Chemical and nonchemical environmental exposures are increasingly
suspected to influence the development of obesity, especially during early life, but studies …

Exposures to pesticides and risk of cancer: evaluation of recent epidemiological evidence in humans and paths forward

H Cavalier, L Trasande, M Porta - International journal of …, 2023 - Wiley Online Library
Abstract Knowledge of the role in cancer etiology of environmental exposures as pesticides
is a prerequisite for primary prevention. We review 63 epidemiological studies on exposure …

Multi-omics profiling approach to asthma: an evolving paradigm

Y Gautam, E Johansson, TB Mersha - Journal of personalized medicine, 2022 - mdpi.com
Asthma is a complex multifactorial and heterogeneous respiratory disease. Although
genetics is a strong risk factor of asthma, external and internal exposures and their …

[HTML][HTML] The early-life exposome: description and patterns in six European countries

I Tamayo-Uria, L Maitre, C Thomsen… - Environment …, 2019 - Elsevier
Abstract Characterization of the “exposome”, the set of all environmental factors that one is
exposed to from conception onwards, has been advocated to better understand the role of …

[HTML][HTML] Machine learning approaches to characterize the obesogenic urban exposome

H Ohanyan, L Portengen, A Huss, E Traini… - Environment …, 2022 - Elsevier
Background Characteristics of the urban environment may contain upstream drivers of
obesity. However, research is lacking that considers the combination of environmental …

[HTML][HTML] Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview

M Vrijheid, X Basagaña, JR Gonzalez… - Environmental …, 2021 - journals.lww.com
Early life stages are vulnerable to environmental hazards and present important windows of
opportunity for lifelong disease prevention. This makes early life a relevant starting point for …

Applying the exposome concept in birth cohort research: a review of statistical approaches

S Santos, L Maitre, C Warembourg, L Agier… - European journal of …, 2020 - Springer
The exposome represents the totality of life course environmental exposures (including
lifestyle and other non-genetic factors), from the prenatal period onwards. This holistic …