Enzymes are a class of natural catalysts with high efficiency, specificity, and selectivity
unmatched by their synthetic counterparts and dictate a myriad of reactions that constitute …

Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Biocatalytic transformations in cells, such as enzyme cascades, involve complex networks
proceeding in spatially confined microenvironments. Here, inspired by nature, we …

DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

The primer-guided entropy-driven high-throughput evolution of the DNA-based
constitutional dynamic network, CDN, is introduced. The entropy gain associated with the …

Multienzymatic cascade reactions are a most important technology to succeed in industrial
process development, such as synthesis of pharmaceutical, cosmetic, and nutritional …

The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

Enzyme catalysis has been attracting increasing interest in the past twenty years.
Nevertheless, most reports concerning enzyme catalysis have been carried out using single …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …