Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment

J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

[HTML][HTML] Re-establishing the comprehension of phytomedicine and nanomedicine in inflammation-mediated cancer signaling

NK Jha, S Arfin, SK Jha, R Kar, A Dey… - Seminars in Cancer …, 2022 - Elsevier
Recent mounting evidence has revealed extensive genetic heterogeneity within tumors that
drive phenotypic variation affecting key cancer pathways, making cancer treatment …

Immune-cell-derived exosomes for cancer therapy

Y Zhao, T Liu, M Zhou - Molecular pharmaceutics, 2022 - ACS Publications
Exosomes are a type of extracellular vesicles secreted by cells in normal or pathological
conditions for cell–cell communication. With immunomodulatory characteristics and potential …

Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy

DN Yadav, MS Ali, AM Thanekar, SV Pogu… - Molecular …, 2022 - ACS Publications
RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …

Effects of curcumin-loaded poly (lactic-co-glycolic acid) nanoparticles in MDA-MB231 human breast cancer cells

A Sharma, S Hawthorne, SK Jha, NK Jha, D Kumar… - …, 2021 - Taylor & Francis
Aim: This study was aimed at evaluating the anticancer potential of curcumin-loaded poly
(lactic-co-glycolic acid)(PLGA) based nanoparticles (NPs) in MDA-MB231 human breast …

[HTML][HTML] Nanocarriers for delivery of siRNA as gene silencing mediator

A Morales-Becerril, L Aranda-Lara, K Isaac-Olivé… - EXCLI …, 2022 - ncbi.nlm.nih.gov
The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

Emerging potential of exosomal non-coding RNA in parkinson's disease: a review

P Zhang, M Rasheed, J Liang, C Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Exosomes are extracellular vesicles that are released by cells and circulate freely in body
fluids. Under physiological and pathological conditions, they serve as cargo for various …

Chitosan nanocarriers for non-coding RNA therapeutics: A review

S Karthik, S Mohan, I Magesh, A Bharathy… - International Journal of …, 2024 - Elsevier
Abstract Non-coding RNA (ncRNA)-based therapies entail delivering ncRNAs to cells to
regulate gene expression and produce proteins that combat infections, cancer, neurological …

Robust Polyion Complex Vesicles (PICsomes) Based on PEO‐b‐poly(amino acid) Copolymers Combining Electrostatic and Hydrophobic Interactions: Formation …

E Aydinlioglu, M Abdelghani, G Le Fer… - Macromolecular …, 2023 - Wiley Online Library
Two pairs of oppositely charged PEO‐b‐poly (amino acid) copolymers with neutral poly
(ethylene oxide) block and polypeptide block composed of the hydrophobic l‐phenylalanine …

Development of novel poly-l-lysine-modified sericin-coated superparamagnetic iron oxide nanoparticles as siRNA carrier

G Kara, S Malekghasemi, B Ozpolat… - Colloids and Surfaces A …, 2021 - Elsevier
Small interfering RNA (siRNA) is a promising therapeutic modality, however, its successful
clinical application is still challenging due to the lack of safe and efficient carrier systems …