Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of
choline results in the production of trimethylamine (TMA), which, upon absorption by the host …

This study employs spectroscopy-based metabolic profiling of fecal extracts from healthy
subjects and patients with active or inactive ulcerative colitis (UC) and Crohn's disease (CD) …

Dietary impacts on health may be one of the oldest concepts in medicine; however, only in
recent years have technical advances in mass spectroscopy, gnotobiology, and bacterial …

Purpose: Metabolomics is a new, rapidly expanding field dedicated to the global study of
metabolites in biological systems. In this article metabolomics is applied to find urinary …

AIM: To evaluate the utility of serum and urine metabolomic analysis in diagnosing and
monitoring of inflammatory bowel diseases (IBD). METHODS: Serum and urine samples …

Metabolomics first burst into the toxicology arena approximately 10–12 years ago,
experiencing rapid growth as a science in the intervening period (Fig. 1). Though …

Objective Anti–tumor necrosis factor (anti‐TNF) therapies are highly effective in rheumatoid
arthritis (RA) and psoriatic arthritis (PsA), but a significant number of patients exhibit only a …

Nuclear magnetic resonance (NMR) spectroscopy and appropriate multivariate statistical
analyses have been employed on mucosal colonic biopsies, colonocytes, lymphocytes, and …

Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour. It is synthesised
from dietary constituents, including choline, L-carnitine, betaine and lecithin by the action of …