Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

SA Streeter, AG Williams, JR Evans, J Wang… - BMC genomics, 2024 - Springer
Background During mitosis the cell depends on proper attachment and segregation of
replicated chromosomes to generate two identical progeny. In cancers defined by …

Determining the impact of WDR5 on the ability of N-MYC to bind chromatin

L Bumpous - 2022 - search.proquest.com
Neuroblastoma is a pediatric cancer of the nervous system, and high-risk patients are known
to have poor prognoses. N-MYC is an oncoprotein transcription factor that is commonly …

[HTML][HTML] Protocol for biallelic tagging of an endogenous gene using CRISPR-Cas9 in human cells

N Kong, YW Chan - STAR protocols, 2023 - Elsevier
We present here a protocol for biallelic tagging of an endogenous gene in human cells
using CRISPR-Cas9 editing technology. Using RIF1 as an example, we describe tagging …