The early, preclinical stages of bovine TB can be detected in live animals by the use of tests
of cellular immunity (the skin, γ-interferon and lymphocyte transformation tests). Tests of …

Existing strategies for long‐term bovine tuberculosis (bTB) control/eradication campaigns
are being reconsidered in many countries because of the development of new testing …

Bovine Tuberculosis (bTB) in cattle is a global health problem and eradication of the disease
requires accurate estimates of diagnostic test performance to optimize their efficiency. The …

ABSTRACT In Great Britain an independent scientific review for the government has
concluded that the development of a cattle vaccine against Mycobacterium bovis infection …

Studies of tuberculosis have suggested a shift in dominance from a T helper type 1 (Th1)
towards a Th2 immune response that is associated with suppressed cell‐mediated immune …

Bovine tuberculosis persists as a costly zoonotic disease in numerous countries despite
extensive eradication and control efforts. Sequential serum samples obtained from …

Diagnostic tests based on cell-mediated immunity are used in programmes for eradication of
bovine tuberculosis (Mycobacterium bovis). Serological assays could be applied as ancillary …

Tuberculosis continues to be a worldwide problem for both humans and animals. The
development of tests to differentiate between infection with Mycobacterium tuberculosis or …

Vaccine development and our understanding of the pathology of bovine tuberculosis in
cattle would be greatly facilitated by definition of the immunological correlates of protection …

Bovine tuberculosis is a major economic problem and a potential public health risk.
Improved diagnostics like the gamma interferon (IFN-γ) test with ESAT6 and/or CFP10 could …