Chronic inflammatory diseases cause profound alterations in tissue homeostasis, including
unchecked activation of immune and nonimmune cells leading to disease complications …

As a highly conserved, multifunctional protein with multiple domains, p62/SQSTM1 plays a
crucial role in several essential cellular activities, particularly selective autophagy. Recent …

Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic
bacteria and thus represent potential targets for antibacterial strategies. Here we focused on …

Investigation of cytoskeleton during bacterial infection has significantly contributed to both
cell and infection biology. Bacterial pathogens Listeria monocytogenes and Shigella flexneri …

Septins are widely recognized as a component of the cytoskeleton that is essential for cell
division, and new work has shown that septins can recognise cell shape by assembling into …

Apoptosis is a form of regulated cell death essential for tissue homeostasis and embryonic
development. Apoptosis also plays a key role during bacterial infection, yet some …

Balanced proliferation and differentiation of neural progenitor cells (NPCs) are critical for
brain development, but how the process is regulated and what components of the cell …

The pathways that induce macroautophagy (referred to as autophagy hereafter) in response
to the stress of starvation are well conserved and essential under nutrient-limiting conditions …

Antibiotic treatment plays an essential role in preventing Shigella infection. However,
incidences of global rise in antibiotic resistance create a major challenge to treat bacterial …

Although it is admitted that secondary infection can complicate viral diseases, the
consequences of viral infection on cell susceptibility to other infections remain …