Dendrimer compositions and methods for drug delivery to the eye

J Cleland, R Sharma, S Appiani - US Patent 11,612,660, 2023 - Google Patents
4, 507466 A 3/1985 Tomalia et al. the treatment or alleviation of one or more symptoms of
the 4,558, 120 A 12 1985 Tomalia et al. diseases of the eye, and/or for diagnosing the …

Selective dendrimer delivery to brain tumors

K Rangaramanujam, BM Tyler, F Zhang… - US Patent …, 2021 - Google Patents
(57) ABSTRACT A composition comprising poly (amidoamine)(PAMAM) hydroxyl-terminated
dendrimers covalently linked to at least one therapeutic, prophylactic or diagnostic agent for …

Dendrimer compositions for use in angiography

K Rangaramanujam, SP Kambhampati, G Lutty… - US Patent …, 2021 - Google Patents
BACKGROUND Fluorescein angiography (FA) and indocyanine green angiography (ICGA)
are widely used in the context of diabetic retinopathy (DR) to verify and locate leakage, and …

Dendrimer delivery system and methods of use thereof

K Rangaramanujam, R Sharma, A Sharma… - US Patent …, 2024 - Google Patents
Low-generation dendrimers containing a high density of surface hydroxyl groups, and
methods of synthesis thereof are provided. In particular, oligo ethylene glycol (OEG)-like …

Dendrimer compositions and methods for drug delivery to the eye

JL Cleland, R Sharma, S Appiani - US Patent 12,121,585, 2024 - Google Patents
US12121585B2 - Dendrimer compositions and methods for drug delivery to the eye - Google
Patents US12121585B2 - Dendrimer compositions and methods for drug delivery to the eye …

Methods of treating severe inflammation

JL Cleland, K Rangaramanujam, S Kannan… - US Patent …, 2024 - Google Patents
(57) ABSTRACT A method for treating or preventing one or more symptoms of severe
inflammation in the lung of a subject in need thereof includes administering to the subject a …

Compositions and methods of enhancing the homing and/or engraftment of hematopoietic cells in the central nervous system

A Filiano, J Kurtzberg, J Kipnis - US Patent 11,679,104, 2023 - Google Patents
US11679104B2 - Compositions and methods of enhancing the homing and/or engraftment of
hematopoietic cells in the central nervous system - Google Patents US11679104B2 …