▪ Abstract Completion of the cell cycle requires the temporal and spatial coordination of
chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding …

A conserved signalling cascade—termed the mitotic-exit network in budding yeast and the
septation-initiation network in fission yeast—controls key events during exit from mitosis and …

Yeast spindle pole bodies (SPBs) duplicate once per cell cycle by a conservative
mechanism resulting in a pre-existing 'old'and a newly formed SPB. The two SPBs of yeast …

During mitosis, a ras-related GTPase (Tem1) binds GTP and activates a signal transduction
pathway to allow mitotic exit. During most of the cell cycle, Tem1 function is antagonized by …

▪ Abstract The mitotic spindle segregates chromosomes to opposite ends of the cell in
preparation for cell division. Chromosome attachment to the spindle is monitored by the …

Productive cell proliferation involves efficient and accurate splitting of the dividing cell into
two separate entities. This orderly process reflects coordination of diverse cytological events …

Peroxisomes are dynamic organelles that often proliferate in response to compounds that
they metabolize. Peroxisomes can proliferate by two apparent mechanisms, division of …

The faithful inheritance of organelles by daughter cells is essential to maintain the benefits
afforded to eukaryotic cells by compartmentalization of biochemical functions. In …

Coordination between the asymmetric partitioning of cell-fate determinants and equal
partitioning of genetic material is crucial to the generation of diverse cell types in a …

For many polarized cells, it is critical that the mitotic spindle becomes positioned relative to
the polarity axis. This is especially important in yeast, where the site of cytokinesis is …