Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …

Calorie restriction is a primary dietary intervention demonstrated over many decades in
cellular and animal models to modulate aging pathways, positively affect age-associated …

Except for latitudes close to the equator, seasonal variation in light hours can change
dramatically between summer and winter. Yet investigations into the interplay between …

The synchronization of circadian clock depends on a central pacemaker located in the
suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central …

Introduction Most mammalian physiology is orchestrated by the circadian clock, including
drug transport and metabolism. As a result, efficacy and toxicity of many drugs are …

Circadian disruption induced by rotating light cycles has been linked to metabolic disorders.
However, how the interaction of light intensity and light cycle affects metabolism under …

Obesity caused by poor eating habits has become a great challenge faced by public health
organizations worldwide. Optimizing dietary intake and ingesting special foods containing …

Abstract Background Nearly 14% of Americans experience chronic circadian disruption due
to shift work, increasing their risk of obesity, diabetes, and other cardiometabolic disorders …

The time of day that we eat is increasingly recognized as contributing as importantly to
overall health as the amount or quality of the food we eat. The endogenous circadian clock …

Diverse animal models have been used to study postpancreatitis diabetes mellitus (PPDM)
development; however, no study has yet conducted a comparative analysis of the specific …