Chalcones: Synthetic chemistry follows where nature leads

HA Jasim, L Nahar, MA Jasim, SA Moore, KJ Ritchie… - Biomolecules, 2021 - mdpi.com
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the
largest groups of bioactive natural products. The potential anticancer, anti-inflammatory …

Mechanism of antibacterial phytoconstituents: An updated review

S Abass, R Parveen, M Irfan, Z Malik, SA Husain… - Archives of …, 2024 - Springer
The increase of multiple drug resistance bacteria significantly diminishes the effectiveness of
antibiotic armory and subsequently exaggerates the level of therapeutic failure …

Chalcone-Acridine Hybrid Suppresses Melanoma Cell Progression via G2/M Cell Cycle Arrest, DNA Damage, Apoptosis, and Modulation of MAP Kinases Activity

M Gazdova, R Michalkova, M Kello, M Vilkova… - International Journal of …, 2022 - mdpi.com
This study was focused on investigating the antiproliferative effects of chalcone hybrids in
melanoma cancer cells. Among seven chalcone hybrids, the chalcone-acridine hybrid 1C …

Photophysical study and biological applications of synthetic chalcone-based fluorescent dyes

S Wangngae, K Chansaenpak, J Nootem, U Ngivprom… - Molecules, 2021 - mdpi.com
A chalcone series (3a–f) with electron push–pull effect was synthesized via a one-pot
Claisen–Schmidt reaction with a simple purification step. The compounds exhibited strong …

[HTML][HTML] Synthesis, α-Glucosidase Inhibitory Activity and Molecular Docking Study of Chalcone Derivatives Bearing a 1H-1, 2, 3-Triazole Unit

B Ardiansah, N Rohman, MAF Nasution… - Chemical and …, 2023 - jstage.jst.go.jp
Diabetes mellitus (DM) is a metabolic condition that is a major health concern around the
world. The current study investigates the synthesis of a series of chalcone and 1H-1, 2, 3 …

Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.

T Maschio-Lima, TH Lemes, MDR Marques… - International …, 2024 - Springer
The scarce antifungal arsenal, changes in the susceptibility profile of fungal agents, and lack
of adherence to treatment have contributed to the increase of cases of dermatomycoses. In …

Methoxy Chalcone Derivatives: Promising Antimicrobial Agents Against Phytopathogens

TAC Santos, C Sousa Ferreira… - Chemistry & …, 2024 - Wiley Online Library
Abstract Chalcone (E)‐1, 3‐diphenyl‐prop‐2‐en‐1‐one and a series of 14 methoxylated
derivatives have been synthesized via Claisen–Schmidt aldol condensation and …

Selectivity and Activity of Benzene‐1,2,4‐triol and its Dimers as Antimicrobial Compounds Against Xanthomonas citri subsp. citri

LB Cavalca, ÚÁ Atlason, A Trofin, CM Ribeiro… - …, 2024 - Wiley Online Library
Citrus canker, caused by the bacterium Xanthomonas citri subsp. citri, is one of the main
threats to citrus fruit production. Several phenolic compounds active against X. citri have …

[PDF][PDF] Chalcones: synthetic chemistry follows where nature leads. Biomolecules. 2021, 11: 1203

HA Jasim, L Nahar, MA Jasim, SA Moore, KJ Ritchie… - 2021 - academia.edu
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the
largest groups of bioactive natural products. The potential anticancer, anti-inflammatory …

Rapid umpolung Michael addition of isatin N, N′-cyclic azomethine imine 1, 3-dipoles with chalcones

G Yue, D Jiang, Z Dou, S Li, J Feng, L Zhang… - New Journal of …, 2021 - pubs.rsc.org
The umpolung Michael addition of isatin N, N′-cyclic azomethine imine 1, 3-dipoles with
chalcones is reported. The reaction could be finished within a very short time (0.3–2 min) …