Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical …
As of May 2022, there have been over 524 million confirmed cases of COVID-19 (10). The pandemic has thus far claimed approximately 6.2 million lives (10). Vaccination is having a …
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of COVID-19. Outline the latest treatments available in the management of COVID-19 …
SA Kemp, DA Collier, RP Datir, IATM Ferreira, S Gayed… - Nature, 2021 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for virus infection through the engagement of the human ACE2 protein and is a major …
P Bégin, J Callum, E Jamula, R Cook, NM Heddle… - Nature medicine, 2021 - nature.com
The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear. Although most randomized controlled trials have shown negative results, uncontrolled …
G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for viral infections owing to characteristics such as their high specificity and their ability to …
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first century, with over one-hundred million infections and over two million deaths to date. It is a …
FK Korley, V Durkalski-Mauldin… - … England Journal of …, 2021 - Mass Medical Soc
Background Early administration of convalescent plasma obtained from blood donors who have recovered from coronavirus disease 2019 (Covid-19) may prevent disease …
W Alhazzani, L Evans, F Alshamsi, MH Møller… - Critical care …, 2021 - journals.lww.com
BACKGROUND: The coronavirus disease 2019 pandemic continues to affect millions worldwide. Given the rapidly growing evidence base, we implemented a living guideline …