[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

[HTML][HTML] Neutralizing monoclonal antibodies for treatment of COVID-19

PC Taylor, AC Adams, MM Hufford… - Nature Reviews …, 2021 - nature.com
Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical …

[PDF][PDF] Therapeutics and COVID-19: living guideline, 14 July 2022

World Health Organization - 2022 - apps.who.int
As of May 2022, there have been over 524 million confirmed cases of COVID-19 (10). The
pandemic has thus far claimed approximately 6.2 million lives (10). Vaccination is having a …

[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)

A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

SARS-CoV-2 evolution during treatment of chronic infection

SA Kemp, DA Collier, RP Datir, IATM Ferreira, S Gayed… - Nature, 2021 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
critical for virus infection through the engagement of the human ACE2 protein and is a major …

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

P Bégin, J Callum, E Jamula, R Cook, NM Heddle… - Nature medicine, 2021 - nature.com
The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear.
Although most randomized controlled trials have shown negative results, uncontrolled …

Antibodies to combat viral infections: development strategies and progress

G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …

COVID-19: breaking down a global health crisis

SI Mallah, OK Ghorab, S Al-Salmi, OS Abdellatif… - Annals of clinical …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

Early convalescent plasma for high-risk outpatients with Covid-19

FK Korley, V Durkalski-Mauldin… - … England Journal of …, 2021 - Mass Medical Soc
Background Early administration of convalescent plasma obtained from blood donors who
have recovered from coronavirus disease 2019 (Covid-19) may prevent disease …

Surviving sepsis campaign guidelines on the management of adults with coronavirus disease 2019 (COVID-19) in the ICU: first update

W Alhazzani, L Evans, F Alshamsi, MH Møller… - Critical care …, 2021 - journals.lww.com
BACKGROUND: The coronavirus disease 2019 pandemic continues to affect millions
worldwide. Given the rapidly growing evidence base, we implemented a living guideline …