Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer

L Buscail, B Bournet, P Cordelier - Nature reviews Gastroenterology & …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is predicted to be the second most common
cause of death within the next 10 years. The prognosis for this disease is poor despite …

The World Health Organization reporting system for pancreaticobiliary cytopathology

MB Pitman, BA Centeno, MD Reid, MT Siddiqui… - Acta Cytologica, 2023 - karger.com
Abstract The World Health Organization (WHO), the International Academy of Cytology, and
the International Agency for Research on Cancer, with expert contributors from around the …

RAS in pancreatic cancer

S Lanfredini, A Thapa, E O'Neill - Biochemical Society …, 2019 - portlandpress.com
The pancreas is a gland composed mainly by endocrine and exocrine cells, giving rise to
three main tumour types. Pancreatic neuroendocrine tumour or PNET arise from the …

Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy

M Sugimori, K Sugimori, H Tsuchiya, Y Suzuki… - Cancer …, 2020 - Wiley Online Library
According to cancer genome sequences, more than 90% of cases of pancreatic ductal
adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables …

Liquid biopsy approach for pancreatic ductal adenocarcinoma

E Buscail, C Maulat, F Muscari, L Chiche, P Cordelier… - Cancers, 2019 - mdpi.com
Pancreatic cancer is a public health problem because of its increasing incidence, the
absence of early diagnostic tools, and its aggressiveness. Despite recent progress in …

EUS tissue acquisition: from A to B

B Kovacevic, P Vilmann - Endoscopic Ultrasound, 2020 - journals.lww.com
EUS-guided tissue acquisition (EUS-TA) has made rapid development since its introduction
in the early 1990s. The technique is widely accepted and invaluable for staging and …

Diagnostic performance of pancreatic cytology with the Papanicolaou Society of Cytopathology System: a systematic review, before shifting into the upcoming WHO …

IP Nikas, T Proctor, S Seide, SS Chatziioannou… - International Journal of …, 2022 - mdpi.com
The Papanicolaou Society of Cytopathology (PSC) reporting system classifies
pancreatobiliary samples into six categories (I–VI), providing guidance for personalized …

Histologic retrieval rate of a newly designed side-bevelled 20G needle for EUS-guided tissue acquisition of solid pancreatic lesions

E Armellini, E Manfrin, E Trisolini… - United European …, 2019 - journals.sagepub.com
Background Innovative approaches to improve diagnostic yield of endoscopic ultrasound-
guided tissue acquisition (EUS-TA) have focused on needle design with development of fine …

[HTML][HTML] Multiplex digital PCR assay to detect multiple KRAS and GNAS mutations associated with pancreatic carcinogenesis from minimal specimen amounts

C Maeda, Y Ono, A Hayashi, K Takahashi… - The Journal of Molecular …, 2023 - Elsevier
Digital PCR (dPCR) allows for highly sensitive quantification of low-frequency mutations and
facilitates early detection of cancer. However, low-throughput targeting of single hotspots in …

Reliable detection of somatic mutations for pancreatic cancer in endoscopic ultrasonography-guided fine needle aspirates with next-generation sequencing …

JR Habib, Y Zhu, L Yin, AA Javed, D Ding… - Journal of …, 2021 - Elsevier
Abstract Background or Purpose Pancreatic ductal adenocarcinoma (PDAC) is commonly
diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). However …