Role of growth factors and cytokines in diabetic foot ulcer healing: a detailed review

M Zubair, J Ahmad - Reviews in Endocrine and Metabolic Disorders, 2019 - Springer
The aim of the review is to examine the role of growth factors and cytokines in the
management of Diabetic Foot Ulcers, such as platelet derived growth factor (PDGF) …

Mechanisms of diabetic foot ulceration: A review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

[HTML][HTML] Multifunctional bioactive core-shell electrospun membrane capable to terminate inflammatory cycle and promote angiogenesis in diabetic wound

K Huang, MS Khalaji, F Yu, X Xie, T Zhu, Y Morsi… - Bioactive materials, 2021 - Elsevier
Diabetic wound (DW) healing is a major clinical challenge due to multifactorial
complications leading to prolonged inflammation. Electrospun nanofibrous (NF) …

What makes wounds chronic

SR Goldberg, RF Diegelmann - Surgical Clinics, 2020 - surgical.theclinics.com
The wound healing process consists of a carefully coordinated sequence of events after a
cutaneous injury leading to regeneration of the skin protective barrier. 1 After an initial insult …

The diabetic foot as a proxy for cardiovascular events and mortality review

I Dietrich, GA Braga, FG de Melo… - Current Atherosclerosis …, 2017 - Springer
Abstract Purpose of Review This article reviewed very recent papers (2016) discussing or
bringing clinical evidences of the possible common pathways leading to diabetic foot …

Therapeutic potential of luteolin on impaired wound healing in streptozotocin-induced rats

LY Chen, HL Cheng, YH Kuan, TJ Liang, YY Chao… - Biomedicines, 2021 - mdpi.com
Long-term hyperglycemia may lead to diabetic microvascular and macrovascular
complications that can affect the peripheral vascular system, particularly in wound healing …

Metabolic memory in diabetic foot syndrome (DFS): MICRO-RNAS, single nucleotide polymorphisms (SNPs) frequency and their relationship with indices of …

A Del Cuore, RM Pipitone, A Casuccio… - Cardiovascular …, 2023 - Springer
Background Diabetic foot is a significant cause of morbidity in diabetic patients, with a rate
that is approximately twice that of patients without foot ulcers.“Metabolic memory” represents …

Functionalized PVA–silk blended nanofibrous mats promote diabetic wound healing via regulation of extracellular matrix and tissue remodelling

D Chouhan, G Janani, B Chakraborty… - Journal of tissue …, 2018 - Wiley Online Library
Chronic cutaneous ulcers, a complex pathophysiological diabetic condition, represent a
critical clinical challenge in the current diabetes mellitus pandemic. Consequently, there is a …

Cellular senescence as the pathogenic hub of diabetes-related wound chronicity

JA Berlanga-Acosta, GE Guillén-Nieto… - Frontiers in …, 2020 - frontiersin.org
Diabetes is constantly increasing at a rate that outpaces genetic variation and approaches to
pandemic magnitude. Skin cells physiology and the cutaneous healing response are …

Magnetic fields as a potential therapy for diabetic wounds based on animal experiments and clinical trials

H Lv, J Liu, C Zhen, Y Wang, Y Wei, W Ren… - Cell …, 2021 - Wiley Online Library
Diabetes mellitus (DM) is a chronic metabolic disorder with various complications that poses
a huge worldwide healthcare burden. Wounds in diabetes, especially diabetic foot ulcers …