Over the years chemotherapy failure has been a vital research topic as researchers have
been striving to discover reasons behind it. The extensive studies carried out on …

Abstract Background Old World cutaneous leishmaniasis (OWCL) is endemic in Iran and
most cases of cutaneous leishmaniasis (CL) are caused by Leishmania major, and then …

Eight new ruthenium complexes of clotrimazole (CTZ) with high antiparasitic activity have
been synthesized, cis, fac-[RuIICl2 (DMSO) 3 (CTZ)](1), cis, cis, trans-[RuIICl2 (DMSO) 2 …

Over the last years, there has been a remarkable increase in the number of unresponsive
patients with anthroponotic cutaneous leishmaniasis (ACL) reported worldwide. The primary …

Leishmaniasis is a neglected and old emerging/reemerging disease that has extremely
increased and expanded in the different geographical areas. Cutaneous leishmaniasis (CL) …

Leishmania, a genus of parasites transmitted to human hosts and mammalian/reptilian
reservoirs by an insect vector, is the causative agent of the human disease complex …

Cutaneous leishmaniasis (CL) is a curable disease; however, due to various risk factors,
unresponsiveness to CL treatments is inevitable. The treatment of CL has been firmly …

The objective of the present study was to compare the host's immune responses between
unresponsive and responsive patients with anthroponotic cutaneous leishmaniasis (ACL) …

Leishmania major is responsible for zoonotic cutaneous leishmaniasis. Therapy is mainly
based on the use of antimony-based drugs; however, treatment failures and illness relapses …

Background Current drug regimens for cutaneous leishmaniasis (CL) include toxic systemic
therapies such as amphotericin B (AB) and pentavalent antimonials. Fluconazole (FZ) is a …