The present review article deals with recent novel studies on the preparation and application
of polyrotaxanes comprised of cyclodextrins (CDs) and various linear polymers, especially …

Due to their controllable size, low cytotoxicity, and unique architecture, cyclodextrin‐based
polyrotaxanes and pseudopolyrotaxanes have been developed to encompass a broad …

Polyrotaxane (PR), in which cyclic molecules are threaded into a linear polymer chain, has
generated great interest because the sliding and rotation of the cyclic molecules on the axial …

Nanoparticle-mediated siRNA delivery is a promising therapeutic approach, however, the
processes required for transport of these materials across the numerous extracellular and …

Various polyrotaxane modification reactions, such as methylation, hydroxy propylation,
tritylation, acetylation, trimethylsilylation, phenylcarbamation, dansylation, and nitration …

To achieve successful delivery of siRNA therapeutics, cytocleavable cationic polyrotaxanes
(PRXs) composed of N, N-dimethylaminoethyl (DMAE) group-modified α-cyclodextrins …

A novel polyrotaxane consisting of poly (dimethylsiloxane)(PDMS) and γ-cyclodextrin (γ-CD)
is synthesized, and the threaded γ-CDs of polyrotaxane are intermolecularly cross-linked in …

Thermoreversible gelation and microphase formation of aqueous solutions of a methylated
polyrotaxane (MePR) were investigated by means of differential scanning microcalorimetry …

The molecular dynamics of condensed polymers are directly linked to practically important
mechanical properties, such as glass transition behavior and impact strength. We present a …

A peculiar rubber elasticity feature of polyrotaxane (PR) gels with cross-links capable of
moving along network strands is revealed by general biaxial strain testing that varies the …