Amantadine in the treatment of Parkinson's disease and other movement disorders

O Rascol, M Fabbri, W Poewe - The Lancet Neurology, 2021 - thelancet.com
The efficacy of amantadine in the symptomatic treatment of patients with Parkinson's
disease, discovered serendipitously more than 50 years ago, has stood the test of time and …

Levodopa-induced dyskinesia in Parkinson's disease: pathogenesis and emerging treatment strategies

DK Kwon, M Kwatra, J Wang, HS Ko - Cells, 2022 - mdpi.com
The most commonly used treatment for Parkinson's disease (PD) is levodopa, prescribed in
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …

[HTML][HTML] Parkinson's disease and its management: part 1: disease entity, risk factors, pathophysiology, clinical presentation, and diagnosis

G DeMaagd, A Philip - Pharmacy and therapeutics, 2015 - ncbi.nlm.nih.gov
Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

Pharmacological treatment of Parkinson disease: a review

BS Connolly, AE Lang - Jama, 2014 - jamanetwork.com
Importance Parkinson disease is the second most common neurodegenerative disease
worldwide. Although no available therapies alter the underlying neurodegenerative process …

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

MF Bastide, WG Meissner, B Picconi, S Fasano… - Progress in …, 2015 - Elsevier
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

The Movement Disorder Society Evidence‐Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease

SH Fox, R Katzenschlager, SY Lim… - Movement …, 2011 - Wiley Online Library
The objective was to update previous evidence‐based medicine reviews of treatments for
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …

Summary of the recommendations of the EFNS/MDS‐ES review on therapeutic management of P arkinson's disease

JJ Ferreira, R Katzenschlager… - European journal of …, 2013 - Wiley Online Library
Objective To summarize the 2010 EFNS/MDS‐ES evidence‐based treatment
recommendations for the management of P arkinson's disease (PD). This summary includes …

Medical and surgical management of advanced Parkinson's disease

A Antonini, E Moro, C Godeiro… - Movement …, 2018 - Wiley Online Library
Advanced Parkinson's disease is characterized by the presence of motor fluctuations,
various degree of dyskinesia, and disability with functional impact on activities of daily living …

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap

P Calabresi, M Di Filippo, V Ghiglieri… - The Lancet …, 2010 - thelancet.com
Levodopa is the most effective drug for the treatment of Parkinson's disease. However, the
long-term use of this dopamine precursor is complicated by highly disabling fluctuations and …

[HTML][HTML] Medical management and prevention of motor complications in Parkinson's disease

SD Aradi, RA Hauser - Neurotherapeutics, 2020 - Elsevier
Levodopa is the most effective medication for the treatment of the motor symptoms of
Parkinson's disease. However, over time, the clinical response to levodopa becomes …