Enoyl acyl carrier protein reductase (InhA) is a key enzyme involved in fatty acid synthesis
mainly mycolic acid biosynthesis that is a part of NADH dependent acyl carrier protein …

Tuberculosis (TB) still continues to be a major killer disease worldwide. Unlike other bacteria
Mycobacterium tuberculosis (Mtb) has the ability to become dormant within the host and to …

Plant diseases caused by phytopathogenic fungi reduce the yield and quality of crops. To
develop novel antifungal agents, we designed and synthesized eight series of …

The studied compound was synthesized by the reaction of diazotized 4-Aminobenzene and
2-amino-4-(4-aminophenyl) thiophene-3-carbonitrile (AATC). The synthesized structure was …

In response to the urgent need to encounter infection diseases, and upon increasing
concerns about the devastating effects of tuberculosis (TB), the promising thiazolidin-4-one …

Herein, an electrocatalytic protocol for the synthesis of 2, 3-dihydroquinazolin-4 (1H)-one
has been disclosed. Methanol is activated and utilized as the C1 source to cyclize with 2 …

N-Formamide synthesis using N-formyl imide with primary and secondary amines with
catalytic amounts of p-toluenesulfonic acid monohydrate (TsOH· H2O) is described. This …

Using a classical hybridization approach, a series of 1H-benzo [d] imidazoles and 3, 4-
dihydroquinazolin-4-ones were synthesized (39 examples) and evaluated as inhibitors of …

Currently available drugs being used to treat leishmaniasis have several shortcomings,
including high toxicity, drug administration that requires hospitalization, and the emergence …

Drug discovery is usually focused on a single protein target; in this process, existing
compounds that bind to related proteins are often ignored. We describe ProBiS plugin …