The sculpting of embryonic tissues and organs into their functional morphologies involves
the spatial and temporal regulation of mechanics at cell and tissue scales. Decades of in …

Biomimetic materials have long been the (he) art of bioengineering. They usually aim at
mimicking in vivo conditions to allow in vitro culture, differentiation and expansion of cells …

Reconstruction of skin equivalents with physiologically relevant cellular and matrix
architecture is indispensable for basic research and industrial applications. As skin-nerve …

Mechanical linkage between cell–cell and cell–extracellular matrix (ECM) adhesions
regulates cell shape changes during embryonic development and tissue homoeostasis. We …

All cells are subjected to mechanical forces throughout their lifetimes. These forces are
sensed by cell surface adhesion receptors and trigger robust actin cytoskeletal …

Aldosterone-producing zona glomerulosa (zG) cells of the adrenal gland arrange in distinct
multi-cellular rosettes that provide a structural framework for adrenal cortex morphogenesis …

Mechanical forces are integral to cellular migration, differentiation and tissue
morphogenesis; however, it has proved challenging to directly measure strain at high spatial …

Cellular tension has implications in normal biology and pathology. Membrane adhesion
receptors serve as conduits for mechanotransduction that lead to cellular responses. Ligand …

As a simple model organism, C. elegans plays an important role in gaining insight into the
relationship between bodily thrashing forces and biological effects, such as disease and …

The anatomic and functional combinations of cusps and lophs (ridges) define the tooth
shape of rodent molars, which distinguishes species. The species-specific cusp patterns …