Immunologic effects of vitamin D on human health and disease

N Charoenngam, MF Holick - Nutrients, 2020 - mdpi.com
Vitamin D is responsible for regulation of calcium and phosphate metabolism and
maintaining a healthy mineralized skeleton. It is also known as an immunomodulatory …

An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Vitamin D: Sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its …

J Janoušek, V Pilařová, K Macáková… - Critical reviews in …, 2022 - Taylor & Francis
Vitamin D has a well-known role in the calcium homeostasis associated with the
maintenance of healthy bones. It increases the efficiency of the intestinal absorption of …

The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention

MF Holick - Reviews in Endocrine and Metabolic Disorders, 2017 - Springer
Vitamin D deficiency and insufficiency is a global health issue that afflicts more than one
billion children and adults worldwide. The consequences of vitamin D deficiency cannot be …

Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects

S Christakos, P Dhawan, A Verstuyf… - Physiological …, 2016 - journals.physiology.org
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

[HTML][HTML] Vitamin D deficiency in Europe: pandemic?

KD Cashman, KG Dowling, Z Škrabáková… - The American journal of …, 2016 - Elsevier
abstract Background: Vitamin D deficiency has been described as being pandemic, but
serum 25-hydroxyvitamin D [25 (OH) D] distribution data for the European Union are of very …

Vitamin D and cardiovascular disease: current evidence and future perspectives

N Cosentino, J Campodonico, V Milazzo, M De Metrio… - Nutrients, 2021 - mdpi.com
Vitamin D deficiency is a prevalent condition, occurring in about 30–50% of the population,
observed across all ethnicities and among all age groups. Besides the established role of …

Global consensus recommendations on prevention and management of nutritional rickets

CF Munns, N Shaw, M Kiely, BL Specker… - The Journal of …, 2016 - academic.oup.com
Background: Vitamin D and calcium deficiencies are common worldwide, causing nutritional
rickets and osteomalacia, which have a major impact on health, growth, and development of …

[HTML][HTML] Sunlight damage to cellular DNA: Focus on oxidatively generated lesions

AP Schuch, NC Moreno, NJ Schuch… - Free Radical Biology …, 2017 - Elsevier
The routine and often unavoidable exposure to solar ultraviolet (UV) radiation makes it one
of the most significant environmental DNA-damaging agents to which humans are exposed …

Vitamin D for health: a global perspective

A Hossein-nezhad, MF Holick - Mayo clinic proceedings, 2013 - Elsevier
It is now generally accepted that vitamin D deficiency is a worldwide health problem that
affects not only musculoskeletal health but also a wide range of acute and chronic diseases …