Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

Activation of endothelium and immune cells is fundamental to the initiation of autoimmune
diseases such as rheumatoid arthritis (RA), and it results in trans-endothelial cell migration …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by local and
systemic inflammation. The complex interplay between immune cells and soluble mediators …

Currently available therapies for rheumatoid arthritis (RA) are inadequate to alleviate the
inflammation and reduce joint damage. While the immune-regulatory effect of human …

In patients with rheumatoid arthritis (RA), intestinal flora imbalance and butyrate metabolism
disorders precede clinical arthritis and are associated with the pathogenesis of RA. This …

Rheumatoid arthritis (RA) is a chronic inflammatory disorder affecting systemic synovial
tissues, leading to the destruction of multiple joints. Its etiology is still unknown, but T-cell …

Background Patients with rheumatoid arthritis (RA) showed impaired immune tolerance
characterized by reduced follicular regulatory T (Tfr) cells, and they also exhibited altered …

Background Increasing evidence indicates a close relationship between alterations in
human immune cells and plasma metabolites with Rheumatoid Arthritis (RA). However …

Objective CD4+ CD8+ T cells are increased in patients with rheumatoid arthritis (RA). They
are not only associated with joint erosions in established disease but are also present in the …