Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways
D Veroutis, OD Argyropoulou, AV Goules… - Annals of the …, 2024 - ard.bmj.com
Objectives Age is the strongest risk factor of giant cell arteritis (GCA), implying a possible
pathogenetic role of cellular senescence. To address this question, we applied an …
pathogenetic role of cellular senescence. To address this question, we applied an …
Current Insights into Tissue Injury of Giant Cell Arteritis: From Acute Inflammatory Responses towards Inappropriate Tissue Remodeling
DA Palamidas, L Chatzis, M Papadaki, I Gissis… - Cells, 2024 - mdpi.com
Giant cell arteritis (GCA) is an autoimmune disease affecting large vessels in patients over
50 years old. It is an exemplary model of a classic inflammatory disorder with IL-6 playing …
50 years old. It is an exemplary model of a classic inflammatory disorder with IL-6 playing …
Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis
W Zhang, Y Zhong, Z Wang, F Tang, C Zheng - Scientific Reports, 2024 - nature.com
The Apple polysaccharides (AP), extracted from the fruit of apple, has been used to treat
multiple pathological diseases. In this study, we evaluated the effects of AP on cognitive …
multiple pathological diseases. In this study, we evaluated the effects of AP on cognitive …
The role of immune aging in giant cell arteritis
P Harkins, S Cowley, R Harrington… - Aging Pathobiology …, 2023 - antpublisher.com
Giant cell arteritis (GCA) is a granulomatous vasculitis with a predilection for medium and
large calibre arteries. The most significant risk factor for its development is advancing age …
large calibre arteries. The most significant risk factor for its development is advancing age …
Vascular disease persistence in giant cell arteritis: are stromal cells neglected?
M Karabayas, HE Ibrahim, AJ Roelofs… - Annals of the …, 2024 - ard.bmj.com
Giant cell arteritis (GCA), the most common systemic vasculitis, is characterised by aberrant
interactions between infiltrating and resident cells of the vessel wall. Ageing and breach of …
interactions between infiltrating and resident cells of the vessel wall. Ageing and breach of …
Inmunosenescencia y autoinmunidad: Mecanismos e implicaciones patológicas
AD Ibarra, J Criado-Villamizar, M Niebles-Navas… - Medicina, 2024 - revistamedicina.net
Las enfermedades autoinmunes son trastornos crónicos caracterizados por la respuesta
inmune del cuerpo contra sus propios tejidos, lo que causa inflamación y daño tisular. La …
inmune del cuerpo contra sus propios tejidos, lo que causa inflamación y daño tisular. La …
Senescent cells in Giant Cell Arteritis have inflammatory phenotype participating in tissue injury via IL-6 dependent pathways
Objectives Age is the strongest risk factor of Giant Cell Arteritis (GCA), implying a possible
pathogenetic role of cellular senescence. To address this question, we applied an …
pathogenetic role of cellular senescence. To address this question, we applied an …
Caracterización de las bases moleculares de la arteritis de células gigantes y otras vasculitis sistémicas mediante una aproximación genómica y transcriptómica
EG Carmona Rubio - 2024 - digibug.ugr.es
Las vasculitis constituyen un grupo heterogéneo de enfermedades inflamatorias que
comprometen los vasos sanguíneos, manifestándose a través de una amplia gama de …
comprometen los vasos sanguíneos, manifestándose a través de una amplia gama de …
[HTML][HTML] Inmunosenescencia y autoinmunidad: Mecanismos e implicaciones patológicas Immunosenescence and autoimmunity: Mechanisms and Pathological …
A David-Ibarra¹, J Criado-Villamizar¹… - revistamedicina.net
Las enfermedades autoinmunes son trastornos crónicos caracterizados por la respuesta
inmune del cuerpo contra sus propios tejidos, lo que causa inflamación y daño tisular. La …
inmune del cuerpo contra sus propios tejidos, lo que causa inflamación y daño tisular. La …