[HTML][HTML] The Lancet Commission on lessons for the future from the COVID-19 pandemic

JD Sachs, SSA Karim, L Aknin, J Allen, K Brosbøl… - The Lancet, 2022 - thelancet.com
Executive summary As of May 31, 2022, there were 6· 9 million reported deaths and 17· 2
million estimated deaths from COVID-19, as reported by the Institute for Health Metrics and …

Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic

M Worobey, JI Levy, L Malpica Serrano… - Science, 2022 - science.org
Understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emerged in 2019 is critical to preventing future zoonotic outbreaks before they become the …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Innate immunity: the first line of defense against SARS-CoV-2

MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus

B Raman, DA Bluemke, TF Lüscher… - European heart …, 2022 - academic.oup.com
Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease
2019 (COVID-19), a condition characterized by the persistence of COVID-19 symptoms …

Risk and protective factors for COVID-19 morbidity, severity, and mortality

J Zhang, X Dong, G Liu, Y Gao - Clinical reviews in allergy & immunology, 2023 - Springer
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global …

The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

JD Domizio, MF Gulen, F Saidoune, VV Thacker… - Nature, 2022 - nature.com
COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …

The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2

JE Pekar, A Magee, E Parker, N Moshiri, K Izhikevich… - Science, 2022 - science.org
Understanding the circumstances that lead to pandemics is important for their prevention.
We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 …

Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines

Q Fernandes, VP Inchakalody, M Merhi… - Annals of …, 2022 - Taylor & Francis
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …