Neuronal loss is one of the striking causes of various central nervous system disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's …
J Yang, J Luo, X Tian, Y Zhao, Y Li, X Wu - Antioxidants, 2024 - mdpi.com
Under normal physiological conditions, reactive oxygen species (ROS) are produced through redox reactions as byproducts of respiratory and metabolic activities. However, due …
Parkinson's disease (PD) is a movement disorder characterized by the progressive degeneration of dopaminergic neurons resulting in dopamine deficiency in the striatum …
Whether neuroinflammation leads to dopaminergic nigrostriatal system neurodegeneration is controversial. We addressed this issue by inducing acute neuroinflammation in the …
NSG Chaves, DE Janner, MR Poetini… - … and Physiology Part C …, 2023 - Elsevier
Abstract β-carotene-loaded nanoparticles improves absorption by increasing bioavailability. The Drosophila melanogaster model of Parkinson's disease must be helpful in investigating …
MV Millán Solano, C Salinas Lara… - International Journal of …, 2023 - mdpi.com
Central nervous system (CNS) infections including meningitis and encephalitis, resulting from the blood-borne spread of specific microorganisms, provoke nervous tissue damage …
HY Li, DS Liu, YB Zhang, H Rong, XJ Zhang - Biophysical Chemistry, 2023 - Elsevier
Parkinson's disease (PD) is an aging-associated neurodegenerative disorder with the hallmark of abnormal aggregates of alpha-synuclein (α-syn) in Lewy bodies (LBs) and Lewy …
Z Zheng, M Chen, S Feng, H Zhao, T Qu, X Zhao… - Cell Death …, 2024 - nature.com
Close correlation between vitamin D (VitD) deficiency and Parkinson's Disease (PD) risk, VitD as an adjuvant treatment promising to improve PD progression. However, VitD …
The astrocyte population, around 50% of human brain cells, plays a crucial role in maintaining the overall health and functionality of the central nervous system (CNS) …