The moment-to-moment processing of information by the nervous system involves the
propagation and interaction of electrical and chemical signals that are distributed in space …

This review covers recent developments in the cellular neurophysiology of retrograde
signaling in the mammalian central nervous system. Normally at a chemical synapse a …

Although extracellular unit recording is typically used for the detection of spike occurrences,
it also has the theoretical ability to report about what are typically considered intracellular …

The hippocampal theta rhythm plays important roles in information processing; however, the
mechanisms of its generation are not well understood. We developed a data-driven …

Spike-frequency adaptation is a prominent feature of neural dynamics. Among other
mechanisms, various ionic currents modulating spike generation cause this type of neural …

The effect of the fluorescent Ca2+ indicator dye Fura-2 on Ca2+ dynamics was studied in
proximal apical dendrites of neocortical layer V and hippocampal CA1 pyramidal neurons in …

1. We have used dendrite‐attached patch‐clamp techniques to record single Na+ and Ca2+
channel activity from the apical dendrites (up to 350 microns away from soma) of CA1 …

Dendritic, backpropagating action potentials (bAPs) facilitate the induction of Hebbian long-
term potentiation (LTP). Although bAPs in distal dendrites of hippocampal CA1 pyramidal …

Wang, Xiao-Jing. Calcium coding and adaptive temporal computation in cortical pyramidal
neurons. J. Neurophysiol. 79: 1549–1566, 1998. In this work, we present a quantitative …

Metabotropic glutamate receptors (mGluRs) can increase intracellular Ca 2+ concentration
via Ins (1, 4, 5) P 3-and ryanodine-sensitive Ca 2+ stores in neurons. Both types of store are …