Antioxidant and prooxidant properties of flavonoids

D Procházková, I Boušová, N Wilhelmová - Fitoterapia, 2011 - Elsevier
The interest in possible health benefits of flavonoids has increased owing to their potent
antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the …

Role of quercetin as an alternative for obesity treatment: you are what you eat!

SF Nabavi, GL Russo, M Daglia, SM Nabavi - Food chemistry, 2015 - Elsevier
Obesity is one of the most serious global health problems, which increases the risk of other
different chronic diseases. The crucial role of oxidative stress in the initiation and …

In Vitro Antioxidant versus Metal Ion Chelating Properties of Flavonoids: A Structure-Activity Investigation

SA Cherrak, N Mokhtari-Soulimane, F Berroukeche… - PloS one, 2016 - journals.plos.org
Natural flavonoids such as quercetin,(+) catechin and rutin as well as four methoxylated
derivatives of quercetin used as models were investigated to elucidate their impact on the …

The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature

TJ Costa, PR Barros, C Arce, JD Santos… - Free Radical Biology …, 2021 - Elsevier
Reactive oxygen and nitrogen species are produced in a wide range of physiological
reactions that, at low concentrations, play essential roles in living organisms. There is a …

Molecular mechanisms of the cardiovascular protective effects of polyphenols

R Andriantsitohaina, C Auger, T Chataigneau… - British Journal of …, 2012 - cambridge.org
Epidemiological studies have reported a greater reduction in cardiovascular risk and
metabolic disorders associated with diets rich in polyphenols. The antioxidant effects of …

Role of food-derived antioxidants against cisplatin induced-nephrotoxicity

T Gómez-Sierra, D Eugenio-Pérez… - Food and Chemical …, 2018 - Elsevier
Cancer is a relevant public health problem that represents the second leading cause of
global death. In this regard, cisplatin is a highly effective antineoplastic drug used in …

Polyphenols: Major regulators of key components of DNA damage response in cancer

M Majidinia, A Bishayee, B Yousefi - DNA repair, 2019 - Elsevier
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …

Polyphenols regulate endothelial functions and reduce the risk of cardiovascular disease

K Yamagata - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Background: Previous studies have shown that intake of polyphenols through the
consumption of vegetables and fruits reduces the risk of Cardiovascular Disease (CVD) by …

Hydroxyl radical scavenging assay of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method using catalase for hydrogen …

M Özyürek, B Bektaşoğlu, K Güçlü, R Apak - Analytica chimica acta, 2008 - Elsevier
Hydroxyl radicals (OH) generated in the human body may play an important role in tissue
injury at sites of inflammation in oxidative stress-originated diseases. As a more convenient …

[HTML][HTML] Exploring the correlation between the molecular structure and biological activities of metal–phenolic compound complexes: research and description of the …

Z Chen, R Świsłocka, R Choińska… - International …, 2024 - pmc.ncbi.nlm.nih.gov
We discussed and summarized the latest data from the global literature on the action of
polyphenolic antioxidants and their metal complexes. The review also includes a summary …