Cytochrome c (Cytc) plays a vital role in the mitochondrial electron transport chain (ETC). In
addition, it is a key regulator of apoptosis. Cytc has multiple other functions including ROS …

Cytochrome c, a protein that belongs to class 1 of the c-type cytochrome family, exerts
different functions depending on its cellular localization and the conditions in which it …

Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

The multifunctional protein cytochrome c (cyt c) plays key roles in electron transport and
apoptosis, switching function by modulating bonding between a heme iron and the sulfur in …

Cytochrome c (cyt c) is a cationic hemoprotein of∼ 100 amino acid residues that exhibits
exceptional functional versatility. While its primary function is electron transfer in the …

In addition to serving as respiratory electron shuttle, ferri-cytochrome c (cyt c) acts as a
peroxidase; ie, it catalyzes the oxidation of organic substrates by H2O2. This peroxidase …

Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several
human pathologies, including neurodegenerative diseases, cardiovascular diseases, and …

Heme proteins are crucial for biological systems by performing diverse functions. Nature has
evolved diverse approaches to fine-tune the structure and function of heme proteins, of …

Cardiolipin oxidation and degradation by different factors under severe cell stress serve as a
trigger for genetically encoded cell death programs. In this context, the interplay between …

The interaction of cytochrome c (Cyt c) with cardiolipin (CL) is believed to play an important
role in the initial events of apoptosis. Herein, we investigate the structural changes of CL …