Ever since the discovery of vaccines, many deadly diseases have been contained
worldwide, ultimately culminating in the eradication of smallpox and polio, which …

Adenoviruses represent the most widely used viral-vectored platform for vaccine design,
showing a great potential in the fight against intracellular infectious diseases to which either …

Background The sudden emergence of novel influenza viruses is a global public health
concern. Conventional influenza vaccines targeting the highly variable surface glycoproteins …

Background The persistent evolution of highly pathogenic avian influenza (HPAI) highlights
the need for novel vaccination techniques that can quickly and effectively respond to …

Replication incompetent human adenovirus serotype 5 (HAdV-C5) has been extensively
used as a delivery vehicle for gene therapy proteins and infectious disease antigens. These …

The recent outbreak of Zika virus (ZIKV) has emerged as a global health concern. ZIKV can
persist in human semen and be transmitted by sexual contact, as well as by mosquitoes, as …

Replication-defective chimpanzee adenovirus vectors are emerging as a promising new
class of genetic vaccine carriers. Chimpanzee adenovirus vectors have now reached the …

It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …

Introduction: Annual vaccination is one of the most efficient and cost-effective strategies to
prevent and control influenza epidemics. Most of the currently available influenza vaccines …

The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a
licensed drug or vaccine to combat the disease and has renewed the urgency to develop a …