Polymerase chain reaction in microfluidic devices
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
Nanotechnology for ultrafast nucleic acid amplification
Nucleic acid detection has been one of the most valued tools in point-of-care diagnostics
from life science, agriculture, food safety and environmental surveillance, because of its high …
from life science, agriculture, food safety and environmental surveillance, because of its high …
Highly multiplexed rapid DNA detection with single-nucleotide specificity via convective PCR in a portable device
Assays for the molecular detection of nucleic acids are typically constrained by the level of
multiplexing (this is the case for the quantitative polymerase chain reaction (qPCR) and for …
multiplexing (this is the case for the quantitative polymerase chain reaction (qPCR) and for …
Cheapstat: An open-source,“do-it-yourself” potentiostat for analytical and educational applications
Although potentiostats are the foundation of modern electrochemical research, they have
seen relatively little application in resource poor settings, such as undergraduate laboratory …
seen relatively little application in resource poor settings, such as undergraduate laboratory …
Gene-Z: a device for point of care genetic testing using a smartphone
By 2012, point of care (POC) testing will constitute roughly one third of the $59 billion in vitro
diagnostics market. The ability to carry out multiplexed genetic testing and wireless …
diagnostics market. The ability to carry out multiplexed genetic testing and wireless …
All-in-one microfluidic device for on-site diagnosis of pathogens based on an integrated continuous flow PCR and electrophoresis biochip
Current continuous flow polymerase chain reaction (CF-PCR) microfluidic chips require
external precision syringe pumps and off-line methods (eg, electrophoresis and …
external precision syringe pumps and off-line methods (eg, electrophoresis and …
Long-range optofluidic control with plasmon heating
B Ciraulo, J Garcia-Guirado, I de Miguel… - Nature …, 2021 - nature.com
Using light to manipulate fluids has been a long-sought-after goal for lab-on-a-chip
applications to address the size mismatch between bulky external fluid controllers and …
applications to address the size mismatch between bulky external fluid controllers and …
Emerging ultrafast nucleic acid amplification technologies for next-generation molecular diagnostics
Over the last decade, nucleic acid amplification tests (NAATs) including polymerase chain
reaction (PCR) were an indispensable methodology for diagnosing cancers, viral and …
reaction (PCR) were an indispensable methodology for diagnosing cancers, viral and …
Handheld real-time PCR device
Here we report one of the smallest real-time polymerase chain reaction (PCR) systems to
date with an approximate size of 100 mm× 60 mm× 33 mm. The system is an autonomous …
date with an approximate size of 100 mm× 60 mm× 33 mm. The system is an autonomous …
Miniaturized nucleic acid amplification systems for rapid and point-of-care diagnostics: a review
F Ahmad, SA Hashsham - Analytica chimica acta, 2012 - Elsevier
Point-of-care (POC) genetic diagnostics critically depends on miniaturization and integration
of sample processing, nucleic acid amplification, and detection systems. Polymerase chain …
of sample processing, nucleic acid amplification, and detection systems. Polymerase chain …