Spirostanes, family of steroidal sapogenins continue to attract attention of organic chemists
due to their easily occurring cleavage reactions in F ring and because of the renaissance of …

Certain steroidal compounds have demonstrated an antiproliferative effect against several
tumor cell lines; however, their complete role on cancer cells is not currently established …

The protected aglycone of saponin OSW-1, a new antitumor natural product, was
synthesized in 13 linear steps in 9.5% overall yield by utilizing the intact skeleton of …

The synthesis of the new glycoside (25R)-3β, 16β-diacetoxy-12, 22-dioxo-5α-cholestan-26-
yl β-d-glucopyranoside starting from hecogenin is described. This compound showed anti …

Using cholesterol and diosgenin as starting materials, we have designed a straightforward
methodology to prepare in a reduced number of steps a novel series of steroidal oximes and …

The MeOH extract of Dracaena viridiflora was found to display significant cytotoxicity against
some cancer cell lines. Systematic phytochemical investigation of this extract led to the …

Sapogenins from the 25R and 25S series show a marked difference on the E/F
regioselectivity of the spiroketal cleavage with BF3/Ac2O. In contrast to the high yield of …

The synthesis and biological evaluation of the new cholestane glycoside (25R)-3β, 16β-
diacetoxy-22-oxocholest-5-en-26-yl β-d-glucopyranoside starting from diosgenin is …

A new transformation of the spiroketal side chain of diosgenin is reported: treatment of 23-
hydroxyiminodiosgenin acetate with phosphorous oxychloride in pyridine produced an …

The new (22R, 23S, 25R)-3β, 16β, 26-triacetoxy-cholest-5-ene-22, 23-diol () was
synthesized from diosgenin () through a synthetic route based on chemoselective RuO4 …