Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …

Liver disease is a leading cause of mortality and morbidity that is rising globally. Liver
dysfunctions are classified into acute and chronic diseases. Various insults, including viral …

Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs)
have been the focus of intense preclinical research and clinical implementation for decades …

Hair follicle-derived mesenchymal stem cells (HF-MSCs) show considerable therapeutic
potential for liver cirrhosis (LC). To improve the effectiveness of naïve HF-MSC treatments on …

Mesenchymal stem cells (MSCs) have emerged as a promising alternative treatment for liver
disease due to their roles in regeneration, fibrosis inhibition, and immunoregulation …

Background Cholesterol accumulation and calcium depletion induce hepatic injury via the
endoplasmic reticulum (ER) stress response. ER stress regulates the calcium imbalance …

Liver transplantation is the only curative option for end-stage liver disease; however, the
limitations of liver transplantation require further research into other alternatives …

Age-related ocular diseases such as age-related macular degeneration, glaucoma, and
diabetic retinopathy are major causes of irreversible vision impairment in the elderly …

Mesenchymal stem cell (MSC) therapy in chronic liver disease is associated with
mitochondrial anaerobic metabolism. Phosphatase of regenerating liver-1 (PRL-1), known …

Aging is a degenerative process involving cell function deterioration, leading to altered
metabolic pathways, increased metabolite diversity, and dysregulated metabolism …