A reward-centred model of anorexia nervosa: a focussed narrative review of the neurological and psychophysiological literature

CB O'Hara, IC Campbell, U Schmidt - Neuroscience & Biobehavioral …, 2015 - Elsevier
This focussed narrative review examines neurobiological and psychophysiological evidence
supporting a role for altered reward processes in the development and maintenance of …

Reward processing in anorexia nervosa

C Keating, AJ Tilbrook, SL Rossell, PG Enticott… - Neuropsychologia, 2012 - Elsevier
Individuals with anorexia nervosa (AN) demonstrate a relentless engagement in behaviors
aimed to reduce their weight, which leads to severe underweight status, and occasionally …

Brain functional alterations in patients with anorexia nervosa: a meta-analysis of task-based functional MRI studies

S Zhong, T Su, J Gong, L Huang, Y Wang - Psychiatry Research, 2023 - Elsevier
The goal of this study was to discern the neural activation patterns associated with anorexia
nervosa (AN) in response to tasks related to body-, food-, emotional-, cognitive-, and reward …

Clinical trials required to assess potential benefits and side effects of treatment of patients with anorexia nervosa with recombinant human leptin

J Hebebrand, G Milos, M Wabitsch, M Teufel… - Frontiers in …, 2019 - frontiersin.org
The core phenotype of anorexia nervosa (AN) comprises the age and stage dependent
intertwining of both its primary and secondary (ie, starvation induced) somatic and mental …

[HTML][HTML] Motivation to eat and not to eat–The psycho-biological conflict in anorexia nervosa

GKW Frank, MC DeGuzman, ME Shott - Physiology & behavior, 2019 - Elsevier
Anorexia nervosa is a severe psychiatric illness with high mortality. Brain imaging research
has indicated altered reward circuits in the disorder. Here we propose a disease model for …

The sedentary (r) evolution: Have we lost our metabolic flexibility?

J Freese, RJ Klement, B Ruiz-Núñez… - …, 2018 - pmc.ncbi.nlm.nih.gov
During the course of evolution, up until the agricultural revolution, environmental fluctuations
forced the human species to develop a flexible metabolism in order to adapt its energy …

[HTML][HTML] Cognitive behavior therapy for eating disorders versus normalization of eating behavior

P Södersten, C Bergh, M Leon, U Brodin… - Physiology & …, 2017 - Elsevier
We examine the science and evidence supporting cognitive behavior therapy (CBT) for the
treatment of bulimia nervosa and other eating disorders. Recent trials focusing on the …

Neurobiology of hyperactivity and reward: agreeable restlessness in anorexia nervosa

AJW Scheurink, GJ Boersma, R Nergårdh… - Physiology & …, 2010 - Elsevier
Restricted food intake is associated with increased physical activity, very likely an
evolutionary advantage, initially both functional and rewarding. The hyperactivity of patients …

Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment

S Paolacci, AK Kiani, E Manara… - Molecular genetics & …, 2020 - Wiley Online Library
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …

Theoretical perspective on anorexia nervosa: the conflict of reward

C Keating - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
This theoretical proposal presents a revised framework for the role of reward in anorexia
nervosa (AN). AN is associated with a fear of weight gain and refusal to maintain a minimally …