Polyvalent snake antivenoms: production strategy and their therapeutic benefits

K Ratanabanangkoon - Toxins, 2023 - mdpi.com
Snake envenomation remains an important yet neglected medical problem in many
countries, with around five million people affected, and over a hundred thousand deaths …

A quest for a universal plasma-derived antivenom against all elapid neurotoxic snake venoms

K Ratanabanangkoon - Frontiers in Immunology, 2021 - frontiersin.org
This review describes the research aimed at the development of universal antivenom
against elapid neurotoxic snake venoms. The antivenoms produced in Thailand in the …

Histopathological Changes in the Liver, Heart and Kidneys Following Malayan Pit Viper (Calloselasma rhodostoma) Envenoming and the Neutralising Effects of …

W Khimmaktong, N Nuanyaem, N Lorthong… - Toxins, 2022 - mdpi.com
Calloselasma rhodostoma (Malayan pit viper) is a medically important snake species that is
widely distributed across Southeast Asia. Systemic coagulopathy causing severe …

[HTML][HTML] Isolation and Pharmacological Characterisation of Pre-Synaptic Neurotoxins from Thai and Javanese Russell's Viper (Daboia siamensis) Venoms

M Lay, WC Hodgson - Toxins, 2024 - mdpi.com
The widespread geographical distribution of Russell's vipers (Daboia spp.) is associated
with marked variations in the clinical outcomes of envenoming by species from different …

A case report of Ovophis monitcola (Mountain pit-viper) envenoming in northeastern India resulting in prolonged coagulopathy

R Ralph, D Garg, A Balachandran, SR Ganesh, T Lamb - Toxicon, 2023 - Elsevier
India is home to a diverse spectrum of medically-significant snakes accounting for one of the
world's largest burdens of envenoming, morbidity and mortality. Indian polyspecific …

Prolonged venom-induced consumptive coagulopathy following Mangshan pit viper (Protobothrops mangshanensis) envenomation despite Hemato Polyvalent …

LTM Wilson, C Dong, A Chambers, S Whitty… - Toxicon, 2024 - Elsevier
This case report summarizes an envenomation by the Mangshan pit viper (Protobothrops
mangshanensis), a rare, endangered, venomous snake endemic to Mount Mang of China …

[HTML][HTML] A Biochemical and Pharmacological Characterization of Phospholipase A2 and Metalloproteinase Fractions from Eastern Russell's Viper (Daboia siamensis …

J Chaisakul, O Khow, K Wiwatwarayos, MRA Rusmili… - Toxins, 2021 - mdpi.com
Acute kidney injury (AKI) following Eastern Russell's viper (Daboia siamensis) envenoming
is a significant symptom in systemically envenomed victims. A number of venom …

Adverse reactions to four types of monovalent antivenom used in the treatment of snakebite envenoming in South China

Q Li, L Zeng, H Deng, Q Liang - Toxicon, 2022 - Elsevier
To evaluate the adverse reactions associated with the four types of monovalent antivenom
currently used in China, we retrospectively analysed the data of all patients admitted for …

In vitro immunoreactivity and in vivo neutralization of Trimeresurus gracilis venom with antivenoms targeting four pit viper species

PC Chuang, JW Chen, YY Chan, TC Tse… - PLOS Neglected …, 2024 - journals.plos.org
Snakebite envenomation is a significant global health issue that requires specific antivenom
treatments. In Taiwan, available antivenoms target a variety of snakes, but none specifically …

In Vitro Toxicity of Chinese Russell's Viper (Daboia siamensis) Venom and Neutralisation by Antivenoms

M Lay, Q Liang, GK Isbister, WC Hodgson - Toxins, 2022 - mdpi.com
Daboia siamensis (Russell's viper) is a highly venomous and medically important snake in
China, as well as much of Asia. There is minimal information on the pharmacological activity …