Cognitive impairment in multiple sclerosis

K Maiese - Bioengineering, 2023 - mdpi.com
Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

[HTML][HTML] Innovative therapeutic strategies for cardiovascular disease

K Maiese - EXCLI journal, 2023 - ncbi.nlm.nih.gov
As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

Cornerstone Cellular pathways for metabolic disorders and Diabetes Mellitus: non-coding RNAs, wnt signaling, and AMPK

K Maiese - Cells, 2023 - mdpi.com
Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …

The implications of telomere length: advanced aging, cell senescence, mri phenotypes, stem cells and alzheimer's disease

K Maiese - Current Neurovascular Research, 2023 - ingentaconnect.com
Telomeres (TLs) reside at the end of chromosomes and are complexes of deoxyribonucleic
acid (DNA). TLs oversee cell replication and the lifespan of a cell, are involved in multiple …

[HTML][HTML] Potential roles of telomeres and telomerase in neurodegenerative diseases

J Shao, J Wang, B Li, C Liu - Ageing and Neurodegenerative …, 2024 - oaepublish.com
Telomeres, essential DNA-protein complexes located at chromosome ends, play a critical
role in preventing chromosome fusion, recombination, and degradation, thus ensuring …

Mind versus body: Perceived stress and biological stress are independently related to cognitive decline

C De Looze, C McCrory, A O'Halloran… - Brain, Behavior, and …, 2024 - Elsevier
Chronic stress may increase risk of age-related cognitive decline.'Stress', however, is a
multidimensional construct and few studies have investigated the inter-relationship of …

c-Jun N-terminal kinase signaling in aging

Y Li, L You, E Nepovimova, V Adam, Z Heger… - Frontiers in Aging …, 2024 - frontiersin.org
Aging encompasses a wide array of detrimental effects that compromise physiological
functions, elevate the risk of chronic diseases, and impair cognitive abilities. However, the …

[HTML][HTML] Association of critically short telomeres with brain and blood markers of ageing and Alzheimer's disease in older adults

A Lehodey, P Kaliman, C Palix… - Alzheimer's …, 2024 - pmc.ncbi.nlm.nih.gov
Background Accumulation of critically short telomeres (CST) is implicated in decreased
tissular regenerative capacity and increased susceptibility to degenerative diseases such as …

Correlation of telomere length in brain tissue with peripheral tissues in living human subjects

AJ Carver, B Hing, BA Elser, SJ Lussier… - Frontiers in Molecular …, 2024 - frontiersin.org
Telomeres are important to chromosomal stability, and changes in their length correlate with
disease, potentially relevant to brain disorders. Assessing telomere length in human brain is …