An overview on the therapeutics of neglected infectious diseases—Leishmaniasis and Chagas diseases

K Chanda - Frontiers in Chemistry, 2021 - frontiersin.org
Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious
diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas …

Traditional application and modern pharmacological research of Artemisia annua L.

X Feng, S Cao, F Qiu, B Zhang - Pharmacology & therapeutics, 2020 - Elsevier
Abstract As a Traditional Chinese Medicine, Artemisia annua L.(A. annua) has been used for
the treatment of various diseases since ancient times, including intermittent fevers due to …

Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

MT Luiz, JSR Viegas, JP Abriata, F Viegas… - European Journal of …, 2021 - Elsevier
Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

Liposomes as multifunctional nano-carriers for medicinal natural products

X Cheng, H Yan, S Pang, M Ya, F Qiu, P Qin… - Frontiers in …, 2022 - frontiersin.org
Although medicinal natural products and their derivatives have shown promising effects in
disease therapies, they usually suffer the drawbacks in low solubility and stability in the …

Sodium stibogluconate loaded nano-deformable liposomes for topical treatment of leishmaniasis: macrophage as a target cell

MJ Dar, FU Din, GM Khan - Drug delivery, 2018 - Taylor & Francis
Topical drug delivery against cutaneous leishmaniasis (CL) signifies an effective alternate
for improving the availability and reducing the toxicity associated with the parenteral …

[HTML][HTML] Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis–A review

P Prasanna, P Kumar, S Kumar, VK Rajana… - Biomedicine & …, 2021 - Elsevier
The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Nitazoxanide and quercetin co-loaded nanotransfersomal gel for topical treatment of cutaneous leishmaniasis with macrophage targeting and enhanced anti …

S Bashir, K Shabbir, F ud Din, SU Khan, Z Ali, BA Khan… - Heliyon, 2023 - cell.com
Purpose Anti-leishmanial medications administered by oral and parenteral routes are less
effective for treatment of cutaneous leishmaniasis (CL) and cause toxicity, hence targeted …

Designing, optimization and characterization of trifluralin transfersomal gel to passively target cutaneous leishmaniasis

AU Khan, H Jamshaid, F ud Din, A Zeb… - Journal of Pharmaceutical …, 2022 - Elsevier
Herein, Trifluralin (TFL) laden transfersomes (TFS) were investigated against Cutaneous
Leishmaniasis (CL), via localized and targeted dermal delivery of TFL. Designed TFL-TFS …

Novel Transethosomal Gel Containing Miconazole Nitrate; Development, Characterization, and Enhanced Antifungal Activity

Z Asghar, T Jamshaid, M Sajid-ur-Rehman… - Pharmaceutics, 2023 - mdpi.com
Miconazole nitrate (MCNR) is a BCS class II antifungal drug with poor water solubility.
Although numerous attempts have been made to increase its solubility, formulation …

Liposomal drug delivery systems for the treatment of leishmaniasis

FF Tuon, LR Dantas, RM de Souza, VST Ribeiro… - Parasitology …, 2022 - Springer
Human le ishmaniasis is a vector-borne, neglected infectious disease that is widely
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …