Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named
Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and …

Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC), are a significant source of morbidity and mortality worldwide. Epidemiological data …

The cannabinoid type two receptors (CB2), an important component of the endocannabinoid
system, have recently emerged as neuromodulators and therapeutic targets for …

The present study aimed to investigate the anti‑ferroptosis effects of the HMGB1 inhibitor
glycyrrhizin (GLY). The present study used a cell and animal model of acute liver failure …

Stroke is considered a leading cause of mortality and neurological disability, which puts a
huge burden on individuals and the community. To date, effective therapy for stroke has …

In 1967, L-dopa was introduced as part of the pharmacological therapy of Parkinson's
disease (PD) and, in spite of extensive research, no additional effective drugs have been …

The blood platelet plays an important role but often remains under‐recognized in several
vascular complications and associated diseases. Surprisingly, platelet hyperactivity and …

Glycyrrhiza glabra L. is a native plant of Central and South-Western Asia that is also diffused
in the Mediterranean area and contains several bioactive compounds such as: flavonoids …

Glycyrrhizin (glycyrrhizic acid), a bioactive triterpenoid saponin constituent of Glycyrrhiza
glabra, is a traditional medicine possessing a plethora of pharmacological anti-inflammatory …