Organoruthenium-bipyridyl complexes–A platform for diverse chemistry and applications

C Pandya, A Sivaramakrishna - Coordination Chemistry Reviews, 2024 - Elsevier
The increasing impact of organometallic complexes of group 8–10 metals academically and
industrially over the years demonstrates remarkable progress in harvesting useful reagents …

Platinum group metal (PGM) complexes having acylthiourea ligand system as catalysts or anticancer agents

S Swaminathan, P Jerome, RJ Deepak… - Coordination Chemistry …, 2024 - Elsevier
The intention behind the design of a metal complex is quite crucial for its development
towards a particular application. Transition metal complexes have tremendously become …

Coordination behavior of acylthiourea ligands in their Ru (II)–benzene complexes─ structures and anticancer activity

S Swaminathan, J Haribabu… - …, 2022 - ACS Publications
Acylthiourea ligands have applications in both synthetic and applied chemistry. The skeleton
of the ligand contains several heteroatoms which offer variable coordination modes in their …

Hinged Bipodal Furoylthiourea-Based Ru(II)-Arene Complexes: Effect of (ortho, meta, or para)-Substitution on Coordination and Anticancer Activity

S Swaminathan, J Haribabu, M Dharmasivam… - Inorganic …, 2023 - ACS Publications
We set out to design and synthesize bipodal ligands with the phenyl group as the spacer
and varied the substitution on the spacer between ortho (L1), meta (L2), and para (L3). The …

Ruthenium (II)–tris-pyrazolylmethane complexes inhibit cancer cell growth by disrupting mitochondrial calcium homeostasis

J Cervinka, A Gobbo, L Biancalana… - Journal of Medicinal …, 2022 - ACS Publications
While ruthenium arene complexes have been widely investigated for their medicinal
potential, studies on homologous compounds containing a tridentate tris (1-pyrazolyl) …

Type I photoreaction and photoinduced ferroptosis by a Ru (II) complex to overcome tumor hypoxia in photodynamic therapy

F Qi, H Yuan, Y Chen, XX Peng, Y Wu, W He… - Ccs …, 2023 - chinesechemsoc.org
Photodynamic therapy (PDT) usually shows limited efficacy in solid tumors since traditional
PDT is O2-dependent while solid tumors are inherently hypoxic. In addition, hypoxic tumor …

Increasing anticancer activity with phosphine ligation in zwitterionic half-sandwich iridium (III), rhodium (III), and ruthenium (II) complexes

X Hu, L Guo, M Liu, Q Zhang, Y Gong, M Sun… - Inorganic …, 2022 - ACS Publications
The synthesis and biological assessment of neutral or cationic platinum group metal-based
anticancer complexes have been extremely studied, whereas there are few reports on the …

Antitumor studies evaluation of triphenylphosphine ruthenium complexes with 5, 7-dihalo-substituted-8-quinolinoline targeting mitophagy pathways

ZF Wang, XQ Huang, RC Wu, Y Xiao… - Journal of Inorganic …, 2023 - Elsevier
Both ruthenium-containing complexes and 8-quinolinoline compounds have emerged as a
potential novel agent for malignant tumor therapy. Here, three triphenylphosphine ruthenium …

Synthesis, spectroscopic characterizations, single crystal X-ray analysis, DFT calculations, in vitro biological evaluation and in silico evaluation studies of …

VNV Palakkeezhillam, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
We created new thiosemicarbazones and their cyclized heterocyclic compounds, examined
them, and evaluated their biological activity in silico and in vitro. Two pyrene-based …

Complexes of ruthenium (II) as promising dual-active agents against cancer and viral infections

A D'Amato, A Mariconda, D Iacopetta, J Ceramella… - Pharmaceuticals, 2023 - mdpi.com
Poor responses to medical care and the failure of pharmacological treatment for many high-
frequency diseases, such as cancer and viral infections, have been widely documented. In …