Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …

The use of cardiovascular implants is commonplace in clinical practice. However,
reproducing the key bioactive and adaptive properties of native cardiovascular tissues with …

Heparin-mimicking polymers have emerged as an alternative to heparin to construct
effective and safe anticoagulant surfaces. However, the present heparin-mimicking polymers …

Tissue-scale architecture and mechanical properties instruct cell behaviour under
physiological and diseased conditions, but our understanding of the underlying mechanisms …

Hydrostatic pressure (HP) and osmotic stress (OS) play an important role in various
biological processes, such as cell proliferation and differentiation. In contrast to canonical …

Aging is the major risk factor for chronic disease development. Cellular senescence is a key
mechanism that triggers or contributes to age-related phenotypes and pathologies. The …

In recent years, more and more metal or non-metal materials have been used in the
treatment of cardiovascular diseases, but the vascular complications after transplantation …

Delayed endothelialization, the excessive proliferation of smooth muscle cells (SMCs), and
persistent inflammation are the main reasons for the implantation failure of blood-contacting …

The primary aim of this article is to review the clinical challenges related to the supply of
power in implanted left ventricular assist devices (LVADs) by means of transcutaneous …

Mechanical forces are of major importance in regulating vascular homeostasis by
influencing endothelial cell behavior and functions. Adherens junctions are critical sites for …